| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10008852 | HBV | ENSG00000115232.14 | protein_coding | ITGA4 | No | No | 3676 | P13612 |
| TVIS30003207 | HIV | ENSG00000115232.14 | protein_coding | ITGA4 | No | No | 3676 | P13612 |
| TVIS30003208 | HIV | ENSG00000115232.14 | protein_coding | ITGA4 | No | No | 3676 | P13612 |
| TVIS30051895 | HIV | ENSG00000115232.14 | protein_coding | ITGA4 | No | No | 3676 | P13612 |
| TVIS30051896 | HIV | ENSG00000115232.14 | protein_coding | ITGA4 | No | No | 3676 | P13612 |
| TVIS30051897 | HIV | ENSG00000115232.14 | protein_coding | ITGA4 | No | No | 3676 | P13612 |
| TVIS20054320 | HPV | ENSG00000115232.14 | protein_coding | ITGA4 | No | No | 3676 | P13612 |
| TVIS20029523 | HPV | ENSG00000115232.14 | protein_coding | ITGA4 | No | No | 3676 | P13612 |
| TVIS20030522 | HPV | ENSG00000115232.14 | protein_coding | ITGA4 | No | No | 3676 | P13612 |
| TVIS20029524 | HPV | ENSG00000115232.14 | protein_coding | ITGA4 | No | No | 3676 | P13612 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ITGA4 |
|---|---|
| DrugBank ID | DB15791 |
| Drug Name | MK-0668 |
| Target ID | BE0010014 |
| UniProt ID | P05556 |
| Regulation Type | |
| PubMed IDs | 19441819 |
| Citations | Lin LS, Lanza T, Jewell JP, Liu P, Jones C, Kieczykowski GR, Treonze K, Si Q, Manior S, Koo G, Tong X, Wang J, Schuelke A, Pivnichny J, Wang R, Raab C, Vincent S, Davies P, Maccoss M, Mumford RA, Hagmann WK: Discovery of N-{N-[(3-cyanophenyl)sulfonyl]-4(R)-cyclobutylamino-(L)-prolyl}-4-[(3',5'-dichlor oisonicotinoyl) amino]-(L)-phenylalanine (MK-0668), an extremely potent and orally active antagonist of very late antigen-4. J Med Chem. 2009 Jun 11;52(11):3449-52. doi: 10.1021/jm900257b. |
| Groups | Experimental |
| Direct Classification | |
| SMILES | OC(=O)[C@H](CC1=CC=C(NC(=O)C2=C(Cl)C=NC=C2Cl)C=C1)NC(=O)[C@@H]1C[C@H](CN1S(=O)(=O)C1=CC=CC(=C1)C#N)NC1CCC1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL506044 |
