Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | TP53 |
|---|---|
| DrugBank ID | DB14548 |
| Drug Name | Zinc sulfate, unspecified form |
| Target ID | BE0003380 |
| UniProt ID | P04637 |
| Regulation Type | chaperone |
| PubMed IDs | 17327663; 29843463 |
| Citations | Wang Y, Rosengarth A, Luecke H: Structure of the human p53 core domain in the absence of DNA. Acta Crystallogr D Biol Crystallogr. 2007 Mar;63(Pt 3):276-81. Epub 2007 Feb 21.@@Kogan S, Carpizo DR: Zinc Metallochaperones as Mutant p53 Reactivators: A New Paradigm in Cancer Therapeutics. Cancers (Basel). 2018 May 29;10(6). pii: cancers10060166. doi: 10.3390/cancers10060166. |
| Groups | Approved; Experimental |
| Direct Classification | |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |