Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20039353HPVENSG00000145863.11protein_codingGABRA6YesNo2559Q16445
TVIS44015037HTLV-1ENSG00000145863.11protein_codingGABRA6YesNo2559Q16445
TCGA Plot Options
Drug Information
GeneGABRA6
DrugBank IDDB00849
Drug NameMethylphenobarbital
Target IDBE0000764
UniProt IDQ16445
Regulation Typepotentiator
PubMed IDs10209232; 11264449; 21194017
CitationsMehta AK, Ticku MK: An update on GABAA receptors. Brain Res Brain Res Rev. 1999 Apr;29(2-3):196-217.@@Yamakura T, Bertaccini E, Trudell JR, Harris RA: Anesthetics and ion channels: molecular models and sites of action. Annu Rev Pharmacol Toxicol. 2001;41:23-51.@@Olsen RW, Li GD: GABA(A) receptors as molecular targets of general anesthetics: identification of binding sites provides clues to allosteric modulation. Can J Anaesth. 2011 Feb;58(2):206-15. doi: 10.1007/s12630-010-9429-7. Epub 2010 Dec 31.
GroupsApproved
Direct ClassificationBarbituric acid derivatives
SMILESCCC1(C(=O)NC(=O)N(C)C1=O)C1=CC=CC=C1
Pathways
PharmGKBPA450374
ChEMBLCHEMBL45029