| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20007244 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20032201 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20046535 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20025051 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20026224 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20018146 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20044758 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20039316 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20046149 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
| TVIS20036822 | HPV | ENSG00000112541.19 | protein_coding | PDE10A | No | No | 10846 | A0A1B1UZR0 Q9Y233 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE10A |
|---|---|
| DrugBank ID | DB08811 |
| Drug Name | Tofisopam |
| Target ID | BE0000631 |
| UniProt ID | Q9Y233 |
| Regulation Type | inhibitor |
| PubMed IDs | 20967473 |
| Citations | Rundfeldt C, Socala K, Wlaz P: The atypical anxiolytic drug, tofisopam, selectively blocks phosphodiesterase isoenzymes and is active in the mouse model of negative symptoms of psychosis. J Neural Transm (Vienna). 2010 Nov;117(11):1319-25. doi: 10.1007/s00702-010-0507-3. Epub 2010 Oct 22. |
| Groups | Experimental |
| Direct Classification | Benzodiazepines |
| SMILES | CCC1C2=CC(OC)=C(OC)C=C2C(=NN=C1C)C1=CC(OC)=C(OC)C=C1 |
| Pathways | |
| PharmGKB | PA165958428 |
| ChEMBL | CHEMBL404216 |
