| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30055939 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055940 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS30055941 | HIV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS20040704 | HPV | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS44043072 | HTLV-1 | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS44048213 | HTLV-1 | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
| TVIS44048233 | HTLV-1 | ENSG00000186951.17 | protein_coding | PPARA | No | No | 5465 | Q07869 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | PPARA |
|---|---|
| DrugBank ID | DB01039 |
| Drug Name | Fenofibrate |
| Target ID | BE0000071 |
| UniProt ID | Q07869 |
| Regulation Type | agonist |
| PubMed IDs | 10494028; 10799317; 11018525; 11342537; 11474486; 11752352; 10828060 |
| Citations | Clavey V, Copin C, Mariotte MC, Bauge E, Chinetti G, Fruchart J, Fruchart JC, Dallongeville J, Staels B: Cell culture conditions determine apolipoprotein CIII secretion and regulation by fibrates in human hepatoma HepG2 cells. Cell Physiol Biochem. 1999;9(3):139-49.@@Chaput E, Saladin R, Silvestre M, Edgar AD: Fenofibrate and rosiglitazone lower serum triglycerides with opposing effects on body weight. Biochem Biophys Res Commun. 2000 May 10;271(2):445-50.@@Casas F, Pineau T, Rochard P, Rodier A, Daury L, Dauca M, Cabello G, Wrutniak-Cabello C: New molecular aspects of regulation of mitochondrial activity by fenofibrate and fasting. FEBS Lett. 2000 Sep 29;482(1-2):71-4.@@Bouly M, Masson D, Gross B, Jiang XC, Fievet C, Castro G, Tall AR, Fruchart JC, Staels B, Lagrost L, Luc G: Induction of the phospholipid transfer protein gene accounts for the high density lipoprotein enlargement in mice treated with fenofibrate. J Biol Chem. 2001 Jul 13;276(28):25841-7. Epub 2001 May 7.@@Dana SL, Hoener PA, Bilakovics JM, Crombie DL, Ogilvie KM, Kauffman RF, Mukherjee R, Paterniti JR Jr: Peroxisome proliferator-activated receptor subtype-specific regulation of hepatic and peripheral gene expression in the Zucker diabetic fatty rat. Metabolism. 2001 Aug;50(8):963-71.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Guerre-Millo M, Gervois P, Raspe E, Madsen L, Poulain P, Derudas B, Herbert JM, Winegar DA, Willson TM, Fruchart JC, Berge RK, Staels B: Peroxisome proliferator-activated receptor alpha activators improve insulin sensitivity and reduce adiposity. J Biol Chem. 2000 Jun 2;275(22):16638-42. |
| Groups | Approved |
| Direct Classification | Benzophenones |
| SMILES | CC(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)C(=O)C1=CC=C(Cl)C=C1 |
| Pathways | |
| PharmGKB | PA449594 |
| ChEMBL | CHEMBL672 |
