| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30074952 | HIV | ENSG00000160179.20 | protein_coding | ABCG1 | No | No | 9619 | P45844 |
| TVIS30081938 | HIV | ENSG00000160179.20 | protein_coding | ABCG1 | No | No | 9619 | P45844 |
| TVIS30083010 | HIV | ENSG00000160179.20 | protein_coding | ABCG1 | No | No | 9619 | P45844 |
| TVIS30054751 | HIV | ENSG00000160179.20 | protein_coding | ABCG1 | No | No | 9619 | P45844 |
| TVIS30054752 | HIV | ENSG00000160179.20 | protein_coding | ABCG1 | No | No | 9619 | P45844 |
| TVIS20002224 | HPV | ENSG00000160179.20 | protein_coding | ABCG1 | No | No | 9619 | P45844 |
| TVIS20023540 | HPV | ENSG00000160179.20 | protein_coding | ABCG1 | No | No | 9619 | P45844 |
| TVIS20056204 | HPV | ENSG00000160179.20 | protein_coding | ABCG1 | No | No | 9619 | P45844 |
| TVIS20045352 | HPV | ENSG00000160179.20 | protein_coding | ABCG1 | No | No | 9619 | P45844 |
| TVIS44005201 | HTLV-1 | ENSG00000160179.20 | protein_coding | ABCG1 | No | No | 9619 | P45844 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ABCG1 |
|---|---|
| DrugBank ID | DB00171 |
| Drug Name | ATP |
| Target ID | BE0001168 |
| UniProt ID | P45844 |
| Regulation Type | |
| PubMed IDs | 16842213; 16876126; 16902423; 17117613; 17158291 |
| Citations | Lage H: MDR1/P-glycoprotein (ABCB1) as target for RNA interference-mediated reversal of multidrug resistance. Curr Drug Targets. 2006 Jul;7(7):813-21.@@Materna V, Stege A, Surowiak P, Priebsch A, Lage H: RNA interference-triggered reversal of ABCC2-dependent cisplatin resistance in human cancer cells. Biochem Biophys Res Commun. 2006 Sep 15;348(1):153-7. Epub 2006 Jul 14.@@Thomas AC, Cullup T, Norgett EE, Hill T, Barton S, Dale BA, Sprecher E, Sheridan E, Taylor AE, Wilroy RS, DeLozier C, Burrows N, Goodyear H, Fleckman P, Stephens KG, Mehta L, Watson RM, Graham R, Wolf R, Slavotinek A, Martin M, Bourn D, Mein CA, O'Toole EA, Kelsell DP: ABCA12 is the major harlequin ichthyosis gene. J Invest Dermatol. 2006 Nov;126(11):2408-13. Epub 2006 Aug 10.@@Girardin F: Membrane transporter proteins: a challenge for CNS drug development. Dialogues Clin Neurosci. 2006;8(3):311-21.@@Pinkett HW, Lee AT, Lum P, Locher KP, Rees DC: An inward-facing conformation of a putative metal-chelate-type ABC transporter. Science. 2007 Jan 19;315(5810):373-7. Epub 2006 Dec 7. |
| Groups | Investigational; Nutraceutical |
| Direct Classification | Purine ribonucleoside triphosphates |
| SMILES | NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |
| Pathways | Glycerolipid Metabolism; Fatty Acid Metabolism; Pamidronate Action Pathway; Simvastatin Action Pathway; Citric Acid Cycle; Glutamate Metabolism; Argininosuccinic Aciduria; Gluconeogenesis; Betaine Metabolism; Butyrate Metabolism; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Rosuvastatin Action Pathway; Propanoate Metabolism; Pentose Phosphate Pathway; Pyruvate Metabolism; Inositol Metabolism; Zoledronate Action Pathway; Glycine and Serine Metabolism; Selenoamino Acid Metabolism; Thiamine Metabolism; Pyrimidine Metabolism; Carbamoyl Phosphate Synthetase Deficiency; Ammonia Recycling; Histidine Metabolism; Pravastatin Action Pathway; Arginine and Proline Metabolism; Starch and Sucrose Metabolism; Purine Metabolism; Fluvastatin Action Pathway; Galactose Metabolism |
| PharmGKB | PA164743471 |
| ChEMBL | CHEMBL14249 |
