| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30043839 | HIV | ENSG00000131473.17 | protein_coding | ACLY | No | No | 47 | P53396 Q4LE36 |
| TVIS20020564 | HPV | ENSG00000131473.17 | protein_coding | ACLY | No | No | 47 | P53396 Q4LE36 |
| TVIS20020565 | HPV | ENSG00000131473.17 | protein_coding | ACLY | No | No | 47 | P53396 Q4LE36 |
| TVIS20020566 | HPV | ENSG00000131473.17 | protein_coding | ACLY | No | No | 47 | P53396 Q4LE36 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | ACLY |
|---|---|
| DrugBank ID | DB11936 |
| Drug Name | Bempedoic acid |
| Target ID | BE0009867 |
| UniProt ID | P53396 |
| Regulation Type | inhibitor |
| PubMed IDs | 29609755; 27663902 |
| Citations | Saeed A, Ballantyne CM: Bempedoic Acid (ETC-1002): A Current Review. Cardiol Clin. 2018 May;36(2):257-264. doi: 10.1016/j.ccl.2017.12.007. Epub 2018 Feb 21.@@Bilen O, Ballantyne CM: Bempedoic Acid (ETC-1002): an Investigational Inhibitor of ATP Citrate Lyase. Curr Atheroscler Rep. 2016 Oct;18(10):61. doi: 10.1007/s11883-016-0611-4. |
| Groups | Approved; Investigational |
| Direct Classification | Long-chain fatty acids |
| SMILES | CC(C)(CCCCCC(O)CCCCCC(C)(C)C(O)=O)C(O)=O |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL3545313 |
