| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10048882 | HBV | ENSG00000196839.14 | protein_coding | ADA | No | No | 100 | A0A0S2Z381 F5GWI4 P00813 |
| TVIS30003290 | HIV | ENSG00000196839.14 | protein_coding | ADA | No | No | 100 | A0A0S2Z381 F5GWI4 P00813 |
| TVIS30007998 | HIV | ENSG00000196839.14 | protein_coding | ADA | No | No | 100 | A0A0S2Z381 F5GWI4 P00813 |
| TVIS30053729 | HIV | ENSG00000196839.14 | protein_coding | ADA | No | No | 100 | A0A0S2Z381 F5GWI4 P00813 |
| TVIS20067170 | HPV | ENSG00000196839.14 | protein_coding | ADA | No | No | 100 | A0A0S2Z381 F5GWI4 P00813 |
| TVIS44018262 | HTLV-1 | ENSG00000196839.14 | protein_coding | ADA | No | No | 100 | A0A0S2Z381 F5GWI4 P00813 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ADA |
|---|---|
| DrugBank ID | DB00552 |
| Drug Name | Pentostatin |
| Target ID | BE0002214 |
| UniProt ID | P00813 |
| Regulation Type | inhibitor |
| PubMed IDs | 11752352; 2433905; 17309302; 10887639 |
| Citations | Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Jackson RC, Leopold WR, Ross DA: The biochemical pharmacology of (2'-R)-chloropentostatin, a novel inhibitor of adenosine deaminase. Adv Enzyme Regul. 1986;25:125-39.@@Newman DJ, Cragg GM: Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.@@Cabanillas F: Purine nucleoside analogs in indolent non-Hodgkin's lymphoma. Oncology (Williston Park). 2000 Jun;14(6 Suppl 2):13-5. |
| Groups | Approved; Investigational |
| Direct Classification | Imidazodiazepines |
| SMILES | OC[C@H]1O[C@H](C[C@@H]1O)N1C=NC2=C1N=CNC[C@H]2O |
| Pathways | |
| PharmGKB | PA450863 |
| ChEMBL | CHEMBL1580 |
