Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10020832HBVENSG00000197894.12protein_codingADH5NoNo128P11766
Q6IRT1
TVIS44004455HTLV-1ENSG00000197894.12protein_codingADH5NoNo128P11766
Q6IRT1
TCGA Plot Options
Drug Information
GeneADH5
DrugBank IDDB00157
Drug NameNADH
Target IDBE0000009
UniProt IDP11766
Regulation Type
PubMed IDs17525463; 17619232; 17092593; 16821840
CitationsSchirwitz K, Schmidt A, Lamzin VS: High-resolution structures of formate dehydrogenase from Candida boidinii. Protein Sci. 2007 Jun;16(6):1146-56.@@Baumchen C, Roth AH, Biedendieck R, Malten M, Follmann M, Sahm H, Bringer-Meyer S, Jahn D: D-mannitol production by resting state whole cell biotrans-formation of D-fructose by heterologous mannitol and formate dehydrogenase gene expression in Bacillus megaterium. Biotechnol J. 2007 Nov;2(11):1408-16.@@Okochi M, Nakagawa I, Kobayashi T, Hayashi S, Furusaki S, Honda H: Enhanced activity of 3alpha-hydroxysteroid dehydrogenase by addition of the co-solvent 1-butyl-3-methylimidazolium (L)-lactate in aqueous phase of biphasic systems for reductive production of steroids. J Biotechnol. 2007 Feb 1;128(2):376-82. Epub 2006 Oct 12.@@Baron R, Lioubashevski O, Katz E, Niazov T, Willner I: Logic gates and elementary computing by enzymes. J Phys Chem A. 2006 Jul 13;110(27):8548-53.
GroupsApproved; Nutraceutical
Direct Classification(5'->5')-dinucleotides
SMILESNC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
PathwaysEthylmalonic Encephalopathy; 3-Methylglutaconic Aciduria Type III; Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency); Caffeine Metabolism; Fructose and Mannose Degradation; Isovaleric Aciduria; Lysine Degradation; Methylmalonic Aciduria Due to Cobalamin-Related Disorders; Glycerol Phosphate Shuttle; Zellweger Syndrome; Propionic Acidemia; Glycolysis; Xanthine Dehydrogenase Deficiency (Xanthinuria); S-Adenosylhomocysteine (SAH) Hydrolase Deficiency; Tryptophan Metabolism; Glutaric Aciduria Type I; 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I; Glycine N-Methyltransferase Deficiency; Dimethylglycine Dehydrogenase Deficiency; Androgen and Estrogen Metabolism; Nucleotide Sugars Metabolism; 3-Methylglutaconic Aciduria Type IV; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Malate-Aspartate Shuttle; Folate Metabolism; Valine, Leucine, and Isoleucine Degradation; Maple Syrup Urine Disease; Glycerol Kinase Deficiency; Adenylosuccinate Lyase Deficiency; Cysteine Metabolism
PharmGKBPA164755085
ChEMBLCHEMBL1234616