| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10057748 | HBV | ENSG00000059573.9 | protein_coding | ALDH18A1 | No | No | 5832 | P54886 |
| TVIS10057747 | HBV | ENSG00000059573.9 | protein_coding | ALDH18A1 | No | No | 5832 | P54886 |
| TVIS10057749 | HBV | ENSG00000059573.9 | protein_coding | ALDH18A1 | No | No | 5832 | P54886 |
| TVIS10059101 | HBV | ENSG00000059573.9 | protein_coding | ALDH18A1 | No | No | 5832 | P54886 |
| TVIS10057755 | HBV | ENSG00000059573.9 | protein_coding | ALDH18A1 | No | No | 5832 | P54886 |
| TVIS10057750 | HBV | ENSG00000059573.9 | protein_coding | ALDH18A1 | No | No | 5832 | P54886 |
| TVIS10057756 | HBV | ENSG00000059573.9 | protein_coding | ALDH18A1 | No | No | 5832 | P54886 |
| TVIS10057757 | HBV | ENSG00000059573.9 | protein_coding | ALDH18A1 | No | No | 5832 | P54886 |
| TVIS10057758 | HBV | ENSG00000059573.9 | protein_coding | ALDH18A1 | No | No | 5832 | P54886 |
| TVIS10057759 | HBV | ENSG00000059573.9 | protein_coding | ALDH18A1 | No | No | 5832 | P54886 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ALDH18A1 |
|---|---|
| DrugBank ID | DB00142 |
| Drug Name | Glutamic acid |
| Target ID | BE0000823 |
| UniProt ID | P54886 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 12513997; 114173; 9622938 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Morita Y, Nakamori S, Takagi H: L-proline accumulation and freeze tolerance of Saccharomyces cerevisiae are caused by a mutation in the PRO1 gene encoding gamma-glutamyl kinase. Appl Environ Microbiol. 2003 Jan;69(1):212-9.@@Krishna RV, Beilstein P, Leisinger T: Biosynthesis of proline in Pseudomonas aeruginosa. Properties of gamma-glutamyl phosphate reductase and 1-pyrroline-5-carboxylate reductase. Biochem J. 1979 Jul 1;181(1):223-30.@@Kamoun P, Aral B, Saudubray JM: [A new inherited metabolic disease: delta1-pyrroline 5-carboxylate synthetase deficiency]. Bull Acad Natl Med. 1998;182(1):131-7; discussion 138-9. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | Histidinemia; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Purine Nucleoside Phosphorylase Deficiency; Tyrosine Metabolism; Ketoprofen Action Pathway; Glutamate Metabolism; Argininosuccinic Aciduria; Salla Disease/Infantile Sialic Acid Storage Disease; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Celecoxib Action Pathway; Glycine and Serine Metabolism; Suprofen Action Pathway; Indomethacin Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Sialuria or French Type Sialuria; Ibuprofen Action Pathway; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Arginine and Proline Metabolism; Purine Metabolism; Diflunisal Action Pathway; Etodolac Action Pathway; Ammonia Recycling |
| PharmGKB | PA449776 |
| ChEMBL | CHEMBL575060 |
