| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30011767 | HIV | ENSG00000120868.15 | protein_coding | APAF1 | No | No | 317 | O14727 |
| TVIS30033844 | HIV | ENSG00000120868.15 | protein_coding | APAF1 | No | No | 317 | O14727 |
| TVIS30033845 | HIV | ENSG00000120868.15 | protein_coding | APAF1 | No | No | 317 | O14727 |
| TVIS30033846 | HIV | ENSG00000120868.15 | protein_coding | APAF1 | No | No | 317 | O14727 |
| TVIS30033847 | HIV | ENSG00000120868.15 | protein_coding | APAF1 | No | No | 317 | O14727 |
| TVIS44026871 | HTLV-1 | ENSG00000120868.15 | protein_coding | APAF1 | No | No | 317 | O14727 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | APAF1 |
|---|---|
| DrugBank ID | DB00171 |
| Drug Name | ATP |
| Target ID | BE0000310 |
| UniProt ID | O14727 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10935465 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Chinnaiyan AM: The apoptosome: heart and soul of the cell death machine. Neoplasia. 1999 Apr;1(1):5-15. |
| Groups | Investigational; Nutraceutical |
| Direct Classification | Purine ribonucleoside triphosphates |
| SMILES | NC1=NC=NC2=C1N=CN2[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O |
| Pathways | Glycerolipid Metabolism; Fatty Acid Metabolism; Pamidronate Action Pathway; Simvastatin Action Pathway; Citric Acid Cycle; Glutamate Metabolism; Argininosuccinic Aciduria; Gluconeogenesis; Betaine Metabolism; Butyrate Metabolism; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Rosuvastatin Action Pathway; Propanoate Metabolism; Pentose Phosphate Pathway; Pyruvate Metabolism; Inositol Metabolism; Zoledronate Action Pathway; Glycine and Serine Metabolism; Selenoamino Acid Metabolism; Thiamine Metabolism; Pyrimidine Metabolism; Carbamoyl Phosphate Synthetase Deficiency; Ammonia Recycling; Histidine Metabolism; Pravastatin Action Pathway; Arginine and Proline Metabolism; Starch and Sucrose Metabolism; Purine Metabolism; Fluvastatin Action Pathway; Galactose Metabolism |
| PharmGKB | PA164743471 |
| ChEMBL | CHEMBL14249 |
