| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30067529 | HIV | ENSG00000070669.17 | protein_coding | ASNS | No | No | 440 | P08243 |
| TVIS30067530 | HIV | ENSG00000070669.17 | protein_coding | ASNS | No | No | 440 | P08243 |
| TVIS20001909 | HPV | ENSG00000070669.17 | protein_coding | ASNS | No | No | 440 | P08243 |
| TVIS44007056 | HTLV-1 | ENSG00000070669.17 | protein_coding | ASNS | No | No | 440 | P08243 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ASNS |
|---|---|
| DrugBank ID | DB00128 |
| Drug Name | Aspartic acid |
| Target ID | BE0000219 |
| UniProt ID | P08243 |
| Regulation Type | substrate |
| PubMed IDs | 27251594 |
| Citations | Yu Q, Wang X, Wang L, Zheng J, Wang J, Wang B: Knockdown of asparagine synthetase (ASNS) suppresses cell proliferation and inhibits tumor growth in gastric cancer cells. Scand J Gastroenterol. 2016 Oct;51(10):1220-6. doi: 10.1080/00365521.2016.1190399. Epub 2016 Jun 2. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Aspartic acid and derivatives |
| SMILES | N[C@@H](CC(O)=O)C(O)=O |
| Pathways | Lesch-Nyhan Syndrome (LNS); Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Xanthinuria Type I; Hyperornithinemia with Gyrate Atrophy (HOGA); Purine Nucleoside Phosphorylase Deficiency; Carnosinuria, Carnosinemia; Tyrosine Metabolism; Disulfiram Action Pathway; Hyperprolinemia Type II; Glutamate Metabolism; Adenine Phosphoribosyltransferase Deficiency (APRT); Mercaptopurine Action Pathway; Argininosuccinic Aciduria; L-Arginine:Glycine Amidinotransferase Deficiency; Xanthine Dehydrogenase Deficiency (Xanthinuria); Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Mitochondrial DNA Depletion Syndrome; Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency; Carbamoyl Phosphate Synthetase Deficiency; Hyperprolinemia Type I; Myoadenylate Deaminase Deficiency; Homocarnosinosis; Malate-Aspartate Shuttle; Arginine and Proline Metabolism; Purine Metabolism; Gout or Kelley-Seegmiller Syndrome; Adenylosuccinate Lyase Deficiency; Ammonia Recycling |
| PharmGKB | PA448494 |
| ChEMBL | CHEMBL274323 |
