| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10033867 | HBV | ENSG00000149311.22 | protein_coding | ATM | No | Yes | 472 | Q13315 |
| TVIS30005962 | HIV | ENSG00000149311.22 | protein_coding | ATM | No | Yes | 472 | Q13315 |
| TVIS30011631 | HIV | ENSG00000149311.22 | protein_coding | ATM | No | Yes | 472 | Q13315 |
| TVIS30001951 | HIV | ENSG00000149311.22 | protein_coding | ATM | No | Yes | 472 | Q13315 |
| TVIS30005963 | HIV | ENSG00000149311.22 | protein_coding | ATM | No | Yes | 472 | Q13315 |
| TVIS30000737 | HIV | ENSG00000149311.22 | protein_coding | ATM | No | Yes | 472 | Q13315 |
| TVIS30014838 | HIV | ENSG00000149311.22 | protein_coding | ATM | No | Yes | 472 | Q13315 |
| TVIS30005964 | HIV | ENSG00000149311.22 | protein_coding | ATM | No | Yes | 472 | Q13315 |
| TVIS30014839 | HIV | ENSG00000149311.22 | protein_coding | ATM | No | Yes | 472 | Q13315 |
| TVIS30014840 | HIV | ENSG00000149311.22 | protein_coding | ATM | No | Yes | 472 | Q13315 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ATM |
|---|---|
| DrugBank ID | DB00201 |
| Drug Name | Caffeine |
| Target ID | BE0004874 |
| UniProt ID | Q13315 |
| Regulation Type | inhibitor |
| PubMed IDs | 10485486; 10531013 |
| Citations | Sarkaria JN, Busby EC, Tibbetts RS, Roos P, Taya Y, Karnitz LM, Abraham RT: Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res. 1999 Sep 1;59(17):4375-82.@@Blasina A, Price BD, Turenne GA, McGowan CH: Caffeine inhibits the checkpoint kinase ATM. Curr Biol. 1999 Oct 7;9(19):1135-8. |
| Groups | Approved |
| Direct Classification | Xanthines |
| SMILES | CN1C=NC2=C1C(=O)N(C)C(=O)N2C |
| Pathways | Caffeine Metabolism |
| PharmGKB | PA448710 |
| ChEMBL | CHEMBL113 |
