| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10035191 | HBV | ENSG00000105409.19 | protein_coding | ATP1A3 | No | No | 478 | P13637 |
| TVIS20033875 | HPV | ENSG00000105409.19 | protein_coding | ATP1A3 | No | No | 478 | P13637 |
| TVIS44007921 | HTLV-1 | ENSG00000105409.19 | protein_coding | ATP1A3 | No | No | 478 | P13637 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | ATP1A3 |
|---|---|
| DrugBank ID | DB01092 |
| Drug Name | Ouabain |
| Target ID | BE0005047 |
| UniProt ID | P13637 |
| Regulation Type | inhibitor |
| PubMed IDs | 24631656 |
| Citations | Weigand KM, Messchaert M, Swarts HG, Russel FG, Koenderink JB: Alternating Hemiplegia of Childhood mutations have a differential effect on Na(+),K(+)-ATPase activity and ouabain binding. Biochim Biophys Acta. 2014 Jul;1842(7):1010-6. doi: 10.1016/j.bbadis.2014.03.002. Epub 2014 Mar 12. |
| Groups | Approved |
| Direct Classification | Cardenolide glycosides and derivatives |
| SMILES | [H][C@@]12CC[C@]3(O)C[C@H](C[C@@H](O)[C@]3(CO)[C@@]1([H])[C@H](O)C[C@]1(C)[C@H](CC[C@]21O)C1=CC(=O)OC1)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O |
| Pathways | |
| PharmGKB | PA163522138 |
| ChEMBL | CHEMBL222863 |
