Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10008168HBVENSG00000138756.19protein_codingBMP2KNoNo55589Q9NSY1
TVIS10041558HBVENSG00000138756.19protein_codingBMP2KNoNo55589Q9NSY1
TVIS30016234HIVENSG00000138756.19protein_codingBMP2KNoNo55589Q9NSY1
TVIS30008599HIVENSG00000138756.19protein_codingBMP2KNoNo55589Q9NSY1
TVIS30085112HIVENSG00000138756.19protein_codingBMP2KNoNo55589Q9NSY1
TVIS30084501HIVENSG00000138756.19protein_codingBMP2KNoNo55589Q9NSY1
TVIS30060239HIVENSG00000138756.19protein_codingBMP2KNoNo55589Q9NSY1
TVIS30021586HIVENSG00000138756.19protein_codingBMP2KNoNo55589Q9NSY1
TVIS30060240HIVENSG00000138756.19protein_codingBMP2KNoNo55589Q9NSY1
TVIS30060241HIVENSG00000138756.19protein_codingBMP2KNoNo55589Q9NSY1
TCGA Plot Options
Drug Information
GeneBMP2K
DrugBank IDDB12010
Drug NameFostamatinib
Target IDBE0009414
UniProt IDQ9NSY1
Regulation Typeinhibitor
PubMed IDs26516587
CitationsRolf MG, Curwen JO, Veldman-Jones M, Eberlein C, Wang J, Harmer A, Hellawell CJ, Braddock M: In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib. Pharmacol Res Perspect. 2015 Oct;3(5):e00175. doi: 10.1002/prp2.175. Epub 2015 Sep 4.
GroupsApproved; Investigational
Direct ClassificationMethoxyanilines
SMILESCOC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC
Pathways
PharmGKB
ChEMBLCHEMBL2103830