| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20009981 | HPV | ENSG00000006283.18 | protein_coding | CACNA1G | No | No | 8913 | O43497 |
| TVIS44042288 | HTLV-1 | ENSG00000006283.18 | protein_coding | CACNA1G | No | No | 8913 | O43497 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1G |
|---|---|
| DrugBank ID | DB00347 |
| Drug Name | Trimethadione |
| Target ID | BE0000483 |
| UniProt ID | O43497 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 17291698; 16171802; 11752352 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Shen H, Zhang B, Shin JH, Lei D, Du Y, Gao X, Wang Q, Ohlemiller KK, Piccirillo J, Bao J: Prophylactic and therapeutic functions of T-type calcium blockers against noise-induced hearing loss. Hear Res. 2007 Apr;226(1-2):52-60. Epub 2006 Dec 31.@@Barton ME, Eberle EL, Shannon HE: The antihyperalgesic effects of the T-type calcium channel blockers ethosuximide, trimethadione, and mibefradil. Eur J Pharmacol. 2005 Oct 3;521(1-3):79-85. Epub 2005 Sep 19.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Oxazolidinediones |
| SMILES | CN1C(=O)OC(C)(C)C1=O |
| Pathways | |
| PharmGKB | PA164744924 |
| ChEMBL | CHEMBL695 |
