| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42000535 | EBV | ENSG00000196557.14 | protein_coding | CACNA1H | No | No | 8912 | A0A1W2PQW2 O95180 |
| TVIS30079906 | HIV | ENSG00000196557.14 | protein_coding | CACNA1H | No | No | 8912 | A0A1W2PQW2 O95180 |
| TVIS30083071 | HIV | ENSG00000196557.14 | protein_coding | CACNA1H | No | No | 8912 | A0A1W2PQW2 O95180 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CACNA1H |
|---|---|
| DrugBank ID | DB00270 |
| Drug Name | Isradipine |
| Target ID | BE0000864 |
| UniProt ID | O95180 |
| Regulation Type | inhibitor |
| PubMed IDs | 1281221; 18974361 |
| Citations | Cohen CJ, Spires S, Van Skiver D: Block of T-type Ca channels in guinea pig atrial cells by antiarrhythmic agents and Ca channel antagonists. J Gen Physiol. 1992 Oct;100(4):703-28.@@Perez-Reyes E, Van Deusen AL, Vitko I: Molecular pharmacology of human Cav3.2 T-type Ca2+ channels: block by antihypertensives, antiarrhythmics, and their analogs. J Pharmacol Exp Ther. 2009 Feb;328(2):621-7. doi: 10.1124/jpet.108.145672. Epub 2008 Oct 30. |
| Groups | Approved; Investigational |
| Direct Classification | Benzoxadiazoles |
| SMILES | COC(=O)C1=C(C)NC(C)=C(C1C1=CC=CC2=NON=C12)C(=O)OC(C)C |
| Pathways | Isradipine Action Pathway |
| PharmGKB | PA450131 |
| ChEMBL | CHEMBL1648 |
