| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018264 | HBV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30007874 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30082824 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30052178 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS30052179 | HIV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS20001238 | HPV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS20055080 | HPV | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS44003313 | HTLV-1 | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
| TVIS44029149 | HTLV-1 | ENSG00000064012.24 | protein_coding | CASP8 | No | Yes | 841 | Q14790 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CASP8 |
|---|---|
| DrugBank ID | DB04297 |
| Drug Name | Trichostatin A |
| Target ID | BE0003460 |
| UniProt ID | Q14790 |
| Regulation Type | activator |
| PubMed IDs | 15809727 |
| Citations | Komata T, Kanzawa T, Nashimoto T, Aoki H, Endo S, Kon T, Takahashi H, Kondo S, Tanaka R: Histone deacetylase inhibitors, N-butyric acid and trichostatin A, induce caspase-8- but not caspase-9-dependent apoptosis in human malignant glioma cells. Int J Oncol. 2005 May;26(5):1345-52. doi: 10.3892/ijo.26.5.1345. |
| Groups | Experimental |
| Direct Classification | Alkyl-phenylketones |
| SMILES | C[C@H](C=C(/C)C=CC(=O)NO)C(=O)C1=CC=C(C=C1)N(C)C |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL99 |
