VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
---|---|---|---|---|---|---|---|---|
TVIS20067251 | HPV | ENSG00000103855.18 | protein_coding | CD276 | Yes | No | 80381 | A0A0C4DGH0 Q5ZPR3 |
TVIS20052411 | HPV | ENSG00000103855.18 | protein_coding | CD276 | Yes | No | 80381 | A0A0C4DGH0 Q5ZPR3 |
TVIS44002273 | HTLV-1 | ENSG00000103855.18 | protein_coding | CD276 | Yes | No | 80381 | A0A0C4DGH0 Q5ZPR3 |
TVIS44027232 | HTLV-1 | ENSG00000103855.18 | protein_coding | CD276 | Yes | No | 80381 | A0A0C4DGH0 Q5ZPR3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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Gene | CD276 |
---|---|
DrugBank ID | DB15635 |
Drug Name | Omburtamab |
Target ID | BE0010140 |
UniProt ID | Q5ZPR3 |
Regulation Type | binder |
PubMed IDs | 26487718 |
Citations | Ahmed M, Cheng M, Zhao Q, Goldgur Y, Cheal SM, Guo HF, Larson SM, Cheung NK: Humanized Affinity-matured Monoclonal Antibody 8H9 Has Potent Antitumor Activity and Binds to FG Loop of Tumor Antigen B7-H3. J Biol Chem. 2015 Dec 11;290(50):30018-29. doi: 10.1074/jbc.M115.679852. Epub 2015 Oct 20. |
Groups | Investigational |
Direct Classification | Peptides |
SMILES | |
Pathways | |
PharmGKB | |
ChEMBL |