| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46000362 | BKPyv | ENSG00000105388.17 | protein_coding | CEACAM5 | No | No | 1048 | A0A024R0K5 P06731 |
| TVIS20007535 | HPV | ENSG00000105388.17 | protein_coding | CEACAM5 | No | No | 1048 | A0A024R0K5 P06731 |
| TVIS20010506 | HPV | ENSG00000105388.17 | protein_coding | CEACAM5 | No | No | 1048 | A0A024R0K5 P06731 |
| TVIS20005068 | HPV | ENSG00000105388.17 | protein_coding | CEACAM5 | No | No | 1048 | A0A024R0K5 P06731 |
| TVIS20005121 | HPV | ENSG00000105388.17 | protein_coding | CEACAM5 | No | No | 1048 | A0A024R0K5 P06731 |
| TVIS20015009 | HPV | ENSG00000105388.17 | protein_coding | CEACAM5 | No | No | 1048 | A0A024R0K5 P06731 |
| TVIS20067898 | HPV | ENSG00000105388.17 | protein_coding | CEACAM5 | No | No | 1048 | A0A024R0K5 P06731 |
| TVIS20025830 | HPV | ENSG00000105388.17 | protein_coding | CEACAM5 | No | No | 1048 | A0A024R0K5 P06731 |
| TVIS20015396 | HPV | ENSG00000105388.17 | protein_coding | CEACAM5 | No | No | 1048 | A0A024R0K5 P06731 |
| TVIS20015008 | HPV | ENSG00000105388.17 | protein_coding | CEACAM5 | No | No | 1048 | A0A024R0K5 P06731 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CEACAM5 |
|---|---|
| DrugBank ID | DB05097 |
| Drug Name | Labetuzumab |
| Target ID | BE0004224 |
| UniProt ID | P06731 |
| Regulation Type | inhibitor |
| PubMed IDs | 19789330 |
| Citations | Govindan SV, Cardillo TM, Moon SJ, Hansen HJ, Goldenberg DM: CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates. Clin Cancer Res. 2009 Oct 1;15(19):6052-61. doi: 10.1158/1078-0432.CCR-09-0586. Epub 2009 Sep 29. |
| Groups | Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | |
| ChEMBL |
