| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10045152 | HBV | ENSG00000095321.18 | protein_coding | CRAT | No | No | 1384 | P43155 |
| TVIS20003890 | HPV | ENSG00000095321.18 | protein_coding | CRAT | No | No | 1384 | P43155 |
| TVIS20003891 | HPV | ENSG00000095321.18 | protein_coding | CRAT | No | No | 1384 | P43155 |
| TVIS20004667 | HPV | ENSG00000095321.18 | protein_coding | CRAT | No | No | 1384 | P43155 |
| TVIS20004248 | HPV | ENSG00000095321.18 | protein_coding | CRAT | No | No | 1384 | P43155 |
| TVIS20003892 | HPV | ENSG00000095321.18 | protein_coding | CRAT | No | No | 1384 | P43155 |
| TVIS20004668 | HPV | ENSG00000095321.18 | protein_coding | CRAT | No | No | 1384 | P43155 |
| TVIS20004249 | HPV | ENSG00000095321.18 | protein_coding | CRAT | No | No | 1384 | P43155 |
| TVIS20003893 | HPV | ENSG00000095321.18 | protein_coding | CRAT | No | No | 1384 | P43155 |
| TVIS20004669 | HPV | ENSG00000095321.18 | protein_coding | CRAT | No | No | 1384 | P43155 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CRAT |
|---|---|
| DrugBank ID | DB00583 |
| Drug Name | Levocarnitine |
| Target ID | BE0000496 |
| UniProt ID | P43155 |
| Regulation Type | |
| PubMed IDs | 12526798; 12562770; 12582227; 15099582; 15155769 |
| Citations | Jogl G, Tong L: Crystal structure of carnitine acetyltransferase and implications for the catalytic mechanism and fatty acid transport. Cell. 2003 Jan 10;112(1):113-22.@@Wu D, Govindasamy L, Lian W, Gu Y, Kukar T, Agbandje-McKenna M, McKenna R: Structure of human carnitine acetyltransferase. Molecular basis for fatty acyl transfer. J Biol Chem. 2003 Apr 11;278(15):13159-65. Epub 2003 Jan 31.@@Vikramadithyan RK, Hiriyan J, Suresh J, Gershome C, Babu RK, Misra P, Rajagopalan R, Chakrabarti R: DRF 2655: a unique molecule that reduces body weight and ameliorates metabolic abnormalities. Obes Res. 2003 Feb;11(2):292-303.@@Govindasamy L, Kukar T, Lian W, Pedersen B, Gu Y, Agbandje-McKenna M, Jin S, McKenna R, Wu D: Structural and mutational characterization of L-carnitine binding to human carnitine acetyltransferase. J Struct Biol. 2004 Jun;146(3):416-24.@@Cordente AG, Lopez-Vinas E, Vazquez MI, Swiegers JH, Pretorius IS, Gomez-Puertas P, Hegardt FG, Asins G, Serra D: Redesign of carnitine acetyltransferase specificity by protein engineering. J Biol Chem. 2004 Aug 6;279(32):33899-908. Epub 2004 May 21. |
| Groups | Approved; Investigational |
| Direct Classification | Carnitines |
| SMILES | C[N+](C)(C)C[C@H](O)CC([O-])=O |
| Pathways | Carnitine Palmitoyl Transferase Deficiency II; Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCAD); Ethylmalonic Encephalopathy; Glutaric Aciduria Type I; Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency); Very-Long-Chain Acyl-CoA Dehydrogenase Deficiency (VLCAD); Carnitine Palmitoyl Transferase Deficiency I; Oxidation of Branched-Chain Fatty Acids; Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids; Fatty Acid Metabolism; Beta Oxidation of Very Long Chain Fatty Acids; Carnitine-Acylcarnitine Translocase Deficiency; Carnitine Synthesis; Trifunctional Protein Deficiency; Adrenoleukodystrophy, X-Linked; Long Chain Acyl-CoA Dehydrogenase Deficiency (LCAD) |
| PharmGKB | PA450154 |
| ChEMBL | CHEMBL1149 |
