| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30087068 | HIV | ENSG00000147571.5 | protein_coding | CRH | No | No | 1392 | A0A0S2Z478 P06850 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CRH |
|---|---|
| DrugBank ID | DB01285 |
| Drug Name | Corticotropin |
| Target ID | BE0001026 |
| UniProt ID | P06850 |
| Regulation Type | agonist |
| PubMed IDs | 16467980; 16472586; 16503922; 16523405; 16534240 |
| Citations | Hellman P, Linder F, Hennings J, Hessman O, Eriksson B, Orlefors H, Akerstrom G: Bilateral adrenalectomy for ectopic Cushing's syndrome-discussions on technique and indication. World J Surg. 2006 May;30(5):909-16.@@Dinan TG, Quigley EM, Ahmed SM, Scully P, O'Brien S, O'Mahony L, O'Mahony S, Shanahan F, Keeling PW: Hypothalamic-pituitary-gut axis dysregulation in irritable bowel syndrome: plasma cytokines as a potential biomarker? Gastroenterology. 2006 Feb;130(2):304-11.@@Zhao LF, Iwasaki Y, Oki Y, Tsugita M, Taguchi T, Nishiyama M, Takao T, Kambayashi M, Hashimoto K: Purinergic receptor ligands stimulate pro-opiomelanocortin gene expression in AtT-20 pituitary corticotroph cells. J Neuroendocrinol. 2006 Apr;18(4):273-8.@@Wagner U, Wahle M, Moritz F, Wagner U, Hantzschel H, Baerwald CG: Promoter polymorphisms regulating corticotrophin-releasing hormone transcription in vitro. Horm Metab Res. 2006 Feb;38(2):69-75.@@Matejec R, Uhlich H, Hotz C, Muhling J, Harbach HW, Bodeker RH, Hempelmann G, Teschemacher H: Corticotropin-releasing hormone reduces pressure pain sensitivity in humans without involvement of beta-endorphin(1-31), but does not reduce heat pain sensitivity. Neuroendocrinology. 2005;82(3-4):185-97. Epub 2006 Mar 13. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA449129 |
| ChEMBL | CHEMBL1201610 |
