| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10015171 | HBV | ENSG00000152207.8 | protein_coding | CYSLTR2 | Yes | No | 57105 | A4ZKH2 Q9NS75 |
| TVIS10005343 | HBV | ENSG00000152207.8 | protein_coding | CYSLTR2 | Yes | No | 57105 | A4ZKH2 Q9NS75 |
| TVIS10027064 | HBV | ENSG00000152207.8 | protein_coding | CYSLTR2 | Yes | No | 57105 | A4ZKH2 Q9NS75 |
| TVIS10027065 | HBV | ENSG00000152207.8 | protein_coding | CYSLTR2 | Yes | No | 57105 | A4ZKH2 Q9NS75 |
| TVIS30083115 | HIV | ENSG00000152207.8 | protein_coding | CYSLTR2 | Yes | No | 57105 | A4ZKH2 Q9NS75 |
| TVIS30035132 | HIV | ENSG00000152207.8 | protein_coding | CYSLTR2 | Yes | No | 57105 | A4ZKH2 Q9NS75 |
| TVIS44005680 | HTLV-1 | ENSG00000152207.8 | protein_coding | CYSLTR2 | Yes | No | 57105 | A4ZKH2 Q9NS75 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | CYSLTR2 |
|---|---|
| DrugBank ID | DB00716 |
| Drug Name | Nedocromil |
| Target ID | BE0000099 |
| UniProt ID | Q9NS75 |
| Regulation Type | antagonist |
| PubMed IDs | 17139284; 17016423; 16164449; 20558817 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Monteseirin J, Chacon P, Vega A, Sanchez-Monteseirin H, Asturias JA, Martinez A, Guardia P, Perez-Cano R, Conde J: L-selectin expression on neutrophils from allergic patients. Clin Exp Allergy. 2005 Sep;35(9):1204-13.@@Yazid S, Leoni G, Getting SJ, Cooper D, Solito E, Perretti M, Flower RJ: Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization. Arterioscler Thromb Vasc Biol. 2010 Sep;30(9):1718-24. doi: 10.1161/ATVBAHA.110.209536. Epub 2010 Jun 17. |
| Groups | Approved; Investigational |
| Direct Classification | Chromenopyridines |
| SMILES | CCCC1=C2N(CC)C(=CC(=O)C2=CC2=C1OC(=CC2=O)C(O)=O)C(O)=O |
| Pathways | |
| PharmGKB | PA450601 |
| ChEMBL | CHEMBL746 |
