| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10005755 | HBV | ENSG00000162496.10 | protein_coding | DHRS3 | No | No | 9249 | O75911 |
| TVIS10005756 | HBV | ENSG00000162496.10 | protein_coding | DHRS3 | No | No | 9249 | O75911 |
| TVIS30005096 | HIV | ENSG00000162496.10 | protein_coding | DHRS3 | No | No | 9249 | O75911 |
| TVIS30001464 | HIV | ENSG00000162496.10 | protein_coding | DHRS3 | No | No | 9249 | O75911 |
| TVIS30014459 | HIV | ENSG00000162496.10 | protein_coding | DHRS3 | No | No | 9249 | O75911 |
| TVIS20015059 | HPV | ENSG00000162496.10 | protein_coding | DHRS3 | No | No | 9249 | O75911 |
| TVIS20015060 | HPV | ENSG00000162496.10 | protein_coding | DHRS3 | No | No | 9249 | O75911 |
| TVIS20015058 | HPV | ENSG00000162496.10 | protein_coding | DHRS3 | No | No | 9249 | O75911 |
| TVIS44024376 | HTLV-1 | ENSG00000162496.10 | protein_coding | DHRS3 | No | No | 9249 | O75911 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | DHRS3 |
|---|---|
| DrugBank ID | DB00162 |
| Drug Name | Vitamin A |
| Target ID | BE0002319 |
| UniProt ID | O75911 |
| Regulation Type | substrate |
| PubMed IDs | 9705317; 11861404; 12697717 |
| Citations | Haeseleer F, Huang J, Lebioda L, Saari JC, Palczewski K: Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal. J Biol Chem. 1998 Aug 21;273(34):21790-9.@@Cerignoli F, Guo X, Cardinali B, Rinaldi C, Casaletto J, Frati L, Screpanti I, Gudas LJ, Gulino A, Thiele CJ, Giannini G: retSDR1, a short-chain retinol dehydrogenase/reductase, is retinoic acid-inducible and frequently deleted in human neuroblastoma cell lines. Cancer Res. 2002 Feb 15;62(4):1196-204.@@Chai Z, Brereton P, Suzuki T, Sasano H, Obeyesekere V, Escher G, Saffery R, Fuller P, Enriquez C, Krozowski Z: 17 beta-hydroxysteroid dehydrogenase type XI localizes to human steroidogenic cells. Endocrinology. 2003 May;144(5):2084-91. |
| Groups | Approved; Nutraceutical; Vet_approved |
| Direct Classification | Retinoids |
| SMILES | CC(=C/CO)C=CC=C(/C)C=CC1=C(C)CCCC1(C)C |
| Pathways | Retinol Metabolism; Vitamin A Deficiency |
| PharmGKB | PA451884 |
| ChEMBL | CHEMBL986 |
