| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10004380 | HBV | ENSG00000049540.19 | protein_coding | ELN | Yes | No | 2006 | B3KRT8 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 |
| TVIS10030858 | HBV | ENSG00000049540.19 | protein_coding | ELN | Yes | No | 2006 | B3KRT8 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 |
| TVIS10051264 | HBV | ENSG00000049540.19 | protein_coding | ELN | Yes | No | 2006 | B3KRT8 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 |
| TVIS10051263 | HBV | ENSG00000049540.19 | protein_coding | ELN | Yes | No | 2006 | B3KRT8 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 |
| TVIS30086929 | HIV | ENSG00000049540.19 | protein_coding | ELN | Yes | No | 2006 | B3KRT8 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 |
| TVIS20002320 | HPV | ENSG00000049540.19 | protein_coding | ELN | Yes | No | 2006 | B3KRT8 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 |
| TVIS44030272 | HTLV-1 | ENSG00000049540.19 | protein_coding | ELN | Yes | No | 2006 | B3KRT8 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 |
| TVIS44019885 | HTLV-1 | ENSG00000049540.19 | protein_coding | ELN | Yes | No | 2006 | B3KRT8 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ELN |
|---|---|
| DrugBank ID | DB00533 |
| Drug Name | Rofecoxib |
| Target ID | BE0001046 |
| UniProt ID | P15502 |
| Regulation Type | other/unknown |
| PubMed IDs | 16679386; 17164475; 17620346 |
| Citations | Oitate M, Hirota T, Koyama K, Inoue S, Kawai K, Ikeda T: Covalent binding of radioactivity from [14C]rofecoxib, but not [14C]celecoxib or [14C]CS-706, to the arterial elastin of rats. Drug Metab Dispos. 2006 Aug;34(8):1417-22. Epub 2006 May 5.@@Oitate M, Hirota T, Takahashi M, Murai T, Miura S, Senoo A, Hosokawa T, Oonishi T, Ikeda T: Mechanism for covalent binding of rofecoxib to elastin of rat aorta. J Pharmacol Exp Ther. 2007 Mar;320(3):1195-203. Epub 2006 Dec 12.@@Oitate M, Hirota T, Murai T, Miura S, Ikeda T: Covalent binding of rofecoxib, but not other cyclooxygenase-2 inhibitors, to allysine aldehyde in elastin of human aorta. Drug Metab Dispos. 2007 Oct;35(10):1846-52. Epub 2007 Jul 9. |
| Groups | Approved; Investigational; Withdrawn |
| Direct Classification | Stilbenes |
| SMILES | CS(=O)(=O)C1=CC=C(C=C1)C1=C(C(=O)OC1)C1=CC=CC=C1 |
| Pathways | Rofecoxib Action Pathway |
| PharmGKB | PA451268 |
| ChEMBL | CHEMBL122 |
