Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10017818HBVENSG00000080224.18protein_codingEPHA6NoNo285220A0A0B4J1T8
Q9UF33
TVIS10005989HBVENSG00000080224.18protein_codingEPHA6NoNo285220A0A0B4J1T8
Q9UF33
TVIS10005988HBVENSG00000080224.18protein_codingEPHA6NoNo285220A0A0B4J1T8
Q9UF33
TVIS10021242HBVENSG00000080224.18protein_codingEPHA6NoNo285220A0A0B4J1T8
Q9UF33
TVIS10042250HBVENSG00000080224.18protein_codingEPHA6NoNo285220A0A0B4J1T8
Q9UF33
TVIS10052075HBVENSG00000080224.18protein_codingEPHA6NoNo285220A0A0B4J1T8
Q9UF33
TVIS10042251HBVENSG00000080224.18protein_codingEPHA6NoNo285220A0A0B4J1T8
Q9UF33
TVIS30013132HIVENSG00000080224.18protein_codingEPHA6NoNo285220A0A0B4J1T8
Q9UF33
TVIS30084048HIVENSG00000080224.18protein_codingEPHA6NoNo285220A0A0B4J1T8
Q9UF33
TVIS30080816HIVENSG00000080224.18protein_codingEPHA6NoNo285220A0A0B4J1T8
Q9UF33
TCGA Plot Options
Drug Information
GeneEPHA6
DrugBank IDDB12010
Drug NameFostamatinib
Target IDBE0009439
UniProt IDQ9UF33
Regulation Typeinhibitor
PubMed IDs26516587
CitationsRolf MG, Curwen JO, Veldman-Jones M, Eberlein C, Wang J, Harmer A, Hellawell CJ, Braddock M: In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib. Pharmacol Res Perspect. 2015 Oct;3(5):e00175. doi: 10.1002/prp2.175. Epub 2015 Sep 4.
GroupsApproved; Investigational
Direct ClassificationMethoxyanilines
SMILESCOC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC
Pathways
PharmGKB
ChEMBLCHEMBL2103830