| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10048681 | HBV | ENSG00000139684.15 | protein_coding | ESD | No | No | 2098 | A0A140VJJ2 P10768 |
| TVIS10048682 | HBV | ENSG00000139684.15 | protein_coding | ESD | No | No | 2098 | A0A140VJJ2 P10768 |
| TVIS30006343 | HIV | ENSG00000139684.15 | protein_coding | ESD | No | No | 2098 | A0A140VJJ2 P10768 |
| TVIS30035087 | HIV | ENSG00000139684.15 | protein_coding | ESD | No | No | 2098 | A0A140VJJ2 P10768 |
| TVIS30035088 | HIV | ENSG00000139684.15 | protein_coding | ESD | No | No | 2098 | A0A140VJJ2 P10768 |
| TVIS30035089 | HIV | ENSG00000139684.15 | protein_coding | ESD | No | No | 2098 | A0A140VJJ2 P10768 |
| TVIS20009155 | HPV | ENSG00000139684.15 | protein_coding | ESD | No | No | 2098 | A0A140VJJ2 P10768 |
| TVIS20009156 | HPV | ENSG00000139684.15 | protein_coding | ESD | No | No | 2098 | A0A140VJJ2 P10768 |
| TVIS20024345 | HPV | ENSG00000139684.15 | protein_coding | ESD | No | No | 2098 | A0A140VJJ2 P10768 |
| TVIS44034393 | HTLV-1 | ENSG00000139684.15 | protein_coding | ESD | No | No | 2098 | A0A140VJJ2 P10768 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ESD |
|---|---|
| DrugBank ID | DB00143 |
| Drug Name | Glutathione |
| Target ID | BE0002283 |
| UniProt ID | P10768 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 12904537; 7397203; 2554783 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Yurimoto H, Lee B, Yano T, Sakai Y, Kato N: Physiological role of S-formylglutathione hydrolase in C(1) metabolism of the methylotrophic yeast Candida boidinii. Microbiology. 2003 Aug;149(Pt 8):1971-9.@@Neben I, Sahm H, Kula MR: Studies on an enzyme, S-formylglutathione hydrolase, of the dissimilatory pathway of methanol in Candida boidinii. Biochim Biophys Acta. 1980 Jul 10;614(1):81-91.@@Sabatier L, Hoffschir F, al Achkar WA, Turleau C, de Grouchy J, Dutrillaux B: The decrease of catalase or esterase D activity in patients with microdeletions of 11p or 13q does not increase their radiosensitivity. Ann Genet. 1989;32(3):144-8. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Peptides |
| SMILES | N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O |
| Pathways | Arachidonic Acid Metabolism; Flurbiprofen Action Pathway; 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency; Oxaprozin Action Pathway; Rofecoxib Action Pathway; Pyruvate Kinase Deficiency; Acetaminophen Metabolism Pathway; Mefenamic Acid Action Pathway; Bromfenac Action Pathway; 5-Oxoprolinuria; gamma-Glutamyltransferase Deficiency; Naproxen Action Pathway; Sulindac Action Pathway; Glutathione Synthetase Deficiency; Piroxicam Action Pathway; Nabumetone Action Pathway; 2-Hydroxyglutric Aciduria (D and L Form); Meloxicam Action Pathway; Cyclophosphamide Action Pathway; Succinic Semialdehyde Dehydrogenase Deficiency; Valdecoxib Action Pathway; Ketorolac Action Pathway; 5-Oxoprolinase Deficiency; Acetylsalicylic Acid Action Pathway; Antipyrine Action Pathway; Glutathione Metabolism; Diclofenac Action Pathway; Homocarnosinosis; Cyclophosphamide Metabolism Pathway; Nepafenac Action Pathway |
| PharmGKB | PA449780 |
| ChEMBL | CHEMBL1543 |
