| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10011938 | HBV | ENSG00000145982.13 | protein_coding | FARS2 | No | No | 10667 | O95363 |
| TVIS10000718 | HBV | ENSG00000145982.13 | protein_coding | FARS2 | No | No | 10667 | O95363 |
| TVIS10039571 | HBV | ENSG00000145982.13 | protein_coding | FARS2 | No | No | 10667 | O95363 |
| TVIS10024638 | HBV | ENSG00000145982.13 | protein_coding | FARS2 | No | No | 10667 | O95363 |
| TVIS10030519 | HBV | ENSG00000145982.13 | protein_coding | FARS2 | No | No | 10667 | O95363 |
| TVIS10051525 | HBV | ENSG00000145982.13 | protein_coding | FARS2 | No | No | 10667 | O95363 |
| TVIS10051526 | HBV | ENSG00000145982.13 | protein_coding | FARS2 | No | No | 10667 | O95363 |
| TVIS30013371 | HIV | ENSG00000145982.13 | protein_coding | FARS2 | No | No | 10667 | O95363 |
| TVIS30010930 | HIV | ENSG00000145982.13 | protein_coding | FARS2 | No | No | 10667 | O95363 |
| TVIS30016353 | HIV | ENSG00000145982.13 | protein_coding | FARS2 | No | No | 10667 | O95363 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | FARS2 |
|---|---|
| DrugBank ID | DB00120 |
| Drug Name | Phenylalanine |
| Target ID | BE0000028 |
| UniProt ID | O95363 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 16969782; 16338408 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Kodama K, Fukuzawa S, Sakamoto K, Nakayama H, Kigawa T, Yabuki T, Matsuda N, Shirouzu M, Takio K, Tachibana K, Yokoyama S: A new protein engineering approach combining chemistry and biology, part I; site-specific incorporation of 4-iodo-L-phenylalanine in vitro by using misacylated suppressor tRNAPhe. Chembiochem. 2006 Oct;7(10):1577-81.@@Kotik-Kogan O, Moor N, Tworowski D, Safro M: Structural basis for discrimination of L-phenylalanine from L-tyrosine by phenylalanyl-tRNA synthetase. Structure. 2005 Dec;13(12):1799-807. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Phenylalanine and derivatives |
| SMILES | N[C@@H](CC1=CC=CC=C1)C(O)=O |
| Pathways | Phenylalanine and Tyrosine Metabolism; Tyrosinemia Type 2 (or Richner-Hanhart Syndrome); Tyrosinemia Type 3 (TYRO3); Phenylketonuria |
| PharmGKB | PA450931 |
| ChEMBL | CHEMBL301523 |
