| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30046696 | HIV | ENSG00000066926.13 | protein_coding | FECH | No | No | 2235 | P22830 |
| TVIS44006504 | HTLV-1 | ENSG00000066926.13 | protein_coding | FECH | No | No | 2235 | P22830 |
| TVIS44021253 | HTLV-1 | ENSG00000066926.13 | protein_coding | FECH | No | No | 2235 | P22830 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FECH |
|---|---|
| DrugBank ID | DB02659 |
| Drug Name | Cholic Acid |
| Target ID | BE0001033 |
| UniProt ID | P22830 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 10592235 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
| Groups | Approved |
| Direct Classification | Trihydroxy bile acids, alcohols and derivatives |
| SMILES | [H][C@@](C)(CCC(O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@]([H])(O)C[C@]4([H])C[C@]([H])(O)CC[C@]4(C)[C@@]3([H])C[C@]([H])(O)[C@]12C |
| Pathways | Congenital Bile Acid Synthesis Defect Type II; Familial Hypercholanemia (FHCA); Bile Acid Biosynthesis; Zellweger Syndrome; Congenital Bile Acid Synthesis Defect Type III; 27-Hydroxylase Deficiency; Cerebrotendinous Xanthomatosis (CTX) |
| PharmGKB | PA166160055 |
| ChEMBL | CHEMBL205596 |
