| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10002882 | HBV | ENSG00000075388.4 | protein_coding | FGF4 | Yes | No | 2249 | P08620 |
| TVIS10022351 | HBV | ENSG00000075388.4 | protein_coding | FGF4 | Yes | No | 2249 | P08620 |
| TVIS10026624 | HBV | ENSG00000075388.4 | protein_coding | FGF4 | Yes | No | 2249 | P08620 |
| TVIS10052528 | HBV | ENSG00000075388.4 | protein_coding | FGF4 | Yes | No | 2249 | P08620 |
| TVIS20021590 | HPV | ENSG00000075388.4 | protein_coding | FGF4 | Yes | No | 2249 | P08620 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FGF4 |
|---|---|
| DrugBank ID | DB00686 |
| Drug Name | Pentosan polysulfate |
| Target ID | BE0000326 |
| UniProt ID | P08620 |
| Regulation Type | inhibitor |
| PubMed IDs | 1279186; 8738610; 1708834 |
| Citations | Zugmaier G, Lippman ME, Wellstein A: Inhibition by pentosan polysulfate (PPS) of heparin-binding growth factors released from tumor cells and blockage by PPS of tumor growth in animals. J Natl Cancer Inst. 1992 Nov 18;84(22):1716-24.@@McLeskey SW, Zhang L, Kharbanda S, Kurebayashi J, Lippman ME, Dickson RB, Kern FG: Fibroblast growth factor overexpressing breast carcinoma cells as models of angiogenesis and metastasis. Breast Cancer Res Treat. 1996;39(1):103-17.@@Wellstein A, Zugmaier G, Califano JA 3rd, Kern F, Paik S, Lippman ME: Tumor growth dependent on Kaposi's sarcoma-derived fibroblast growth factor inhibited by pentosan polysulfate. J Natl Cancer Inst. 1991 May 15;83(10):716-20. |
| Groups | Approved |
| Direct Classification | O-glycosyl compounds |
| SMILES | O[C@@H]1CO[C@@H](O[C@@H]2CO[C@@H](O)[C@H](OS(O)(=O)=O)[C@H]2OS(O)(=O)=O)[C@H](OS(O)(=O)=O)[C@H]1OS(O)(=O)=O |
| Pathways | |
| PharmGKB | PA164774806 |
| ChEMBL | CHEMBL4073796 |
