| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10038413 | HBV | ENSG00000000938.13 | protein_coding | FGR | No | No | 2268 | P09769 |
| TVIS30074496 | HIV | ENSG00000000938.13 | protein_coding | FGR | No | No | 2268 | P09769 |
| TVIS30074497 | HIV | ENSG00000000938.13 | protein_coding | FGR | No | No | 2268 | P09769 |
| TVIS30079787 | HIV | ENSG00000000938.13 | protein_coding | FGR | No | No | 2268 | P09769 |
| TVIS30022806 | HIV | ENSG00000000938.13 | protein_coding | FGR | No | No | 2268 | P09769 |
| TVIS30022807 | HIV | ENSG00000000938.13 | protein_coding | FGR | No | No | 2268 | P09769 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FGR |
|---|---|
| DrugBank ID | DB01254 |
| Drug Name | Dasatinib |
| Target ID | BE0005539 |
| UniProt ID | P09769 |
| Regulation Type | inhibitor |
| PubMed IDs | 18180381; 17154512 |
| Citations | Kneidinger M, Schmidt U, Rix U, Gleixner KV, Vales A, Baumgartner C, Lupinek C, Weghofer M, Bennett KL, Herrmann H, Schebesta A, Thomas WR, Vrtala S, Valenta R, Lee FY, Ellmeier W, Superti-Furga G, Valent P: The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils. Blood. 2008 Mar 15;111(6):3097-107. doi: 10.1182/blood-2007-08-104372. Epub 2008 Jan 7.@@Das J, Chen P, Norris D, Padmanabha R, Lin J, Moquin RV, Shen Z, Cook LS, Doweyko AM, Pitt S, Pang S, Shen DR, Fang Q, de Fex HF, McIntyre KW, Shuster DJ, Gillooly KM, Behnia K, Schieven GL, Wityak J, Barrish JC: 2-aminothiazole as a novel kinase inhibitor template. Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1- piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (dasatinib, BMS-354825) as a potent pan-Src kinase inhibitor. J Med Chem. 2006 Nov 16;49(23):6819-32. |
| Groups | Approved; Investigational |
| Direct Classification | Aromatic anilides |
| SMILES | CC1=NC(NC2=NC=C(S2)C(=O)NC2=C(C)C=CC=C2Cl)=CC(=N1)N1CCN(CCO)CC1 |
| Pathways | Dasatinib Inhibition of BCR-ABL |
| PharmGKB | PA162372878 |
| ChEMBL | CHEMBL1421 |
