| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017816 | HBV | ENSG00000160282.15 | protein_coding | FTCD | No | No | 10841 | O95954 |
| TVIS10007942 | HBV | ENSG00000160282.15 | protein_coding | FTCD | No | No | 10841 | O95954 |
| TVIS10017853 | HBV | ENSG00000160282.15 | protein_coding | FTCD | No | No | 10841 | O95954 |
| TVIS10013906 | HBV | ENSG00000160282.15 | protein_coding | FTCD | No | No | 10841 | O95954 |
| TVIS10005985 | HBV | ENSG00000160282.15 | protein_coding | FTCD | No | No | 10841 | O95954 |
| TVIS10033585 | HBV | ENSG00000160282.15 | protein_coding | FTCD | No | No | 10841 | O95954 |
| TVIS10047015 | HBV | ENSG00000160282.15 | protein_coding | FTCD | No | No | 10841 | O95954 |
| TVIS10059084 | HBV | ENSG00000160282.15 | protein_coding | FTCD | No | No | 10841 | O95954 |
| TVIS10059097 | HBV | ENSG00000160282.15 | protein_coding | FTCD | No | No | 10841 | O95954 |
| TVIS10059098 | HBV | ENSG00000160282.15 | protein_coding | FTCD | No | No | 10841 | O95954 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | FTCD |
|---|---|
| DrugBank ID | DB00116 |
| Drug Name | Tetrahydrofolic acid |
| Target ID | BE0000822 |
| UniProt ID | O95954 |
| Regulation Type | cofactor |
| PubMed IDs | 9677387; 11488596; 10329787; 10673422 |
| Citations | Bashour AM, Bloom GS: 58K, a microtubule-binding Golgi protein, is a formiminotransferase cyclodeaminase. J Biol Chem. 1998 Jul 31;273(31):19612-7.@@Cook RJ: Disruption of histidine catabolism in NEUT2 mice. Arch Biochem Biophys. 2001 Aug 15;392(2):226-32.@@Kohls D, Croteau N, Mejia N, MacKenzie RE, Vrielink A: Crystallization and preliminary X-ray analysis of the formiminotransferase domain from the bifunctional enzyme formiminotransferase-cyclodeaminase. Acta Crystallogr D Biol Crystallogr. 1999 Jun;55(Pt 6):1206-8.@@Kohls D, Sulea T, Purisima EO, MacKenzie RE, Vrielink A: The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: implications for substrate channeling in a bifunctional enzyme. Structure. 2000 Jan 15;8(1):35-46. |
| Groups | Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1 |
| Pathways | Histidinemia; Lesch-Nyhan Syndrome (LNS); Molybdenum Cofactor Deficiency; Azathioprine Action Pathway; AICA-Ribosiduria; Purine Nucleoside Phosphorylase Deficiency; Methionine Adenosyltransferase Deficiency; Folate Malabsorption, Hereditary; Adenine Phosphoribosyltransferase Deficiency (APRT); Thioguanine Action Pathway; Mercaptopurine Action Pathway; Non-Ketotic Hyperglycinemia; Methotrexate Action Pathway; Betaine Metabolism; S-Adenosylhomocysteine (SAH) Hydrolase Deficiency; Glycine and Serine Metabolism; Adenosine Deaminase Deficiency; Xanthinuria Type II; Methionine Metabolism; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Histidine Metabolism; Cystathionine beta-Synthase Deficiency; Folate Metabolism; Sarcosine Oncometabolite Pathway; Sarcosinemia; Methylenetetrahydrofolate Reductase Deficiency (MTHFRD); Purine Metabolism; Gout or Kelley-Seegmiller Syndrome; Adenylosuccinate Lyase Deficiency; Ammonia Recycling |
| PharmGKB | PA164745110 |
| ChEMBL | CHEMBL2021342 |
