| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42001169 | EBV | ENSG00000111640.15 | protein_coding | GAPDH | No | No | 2597 | P04406 |
| TVIS10012770 | HBV | ENSG00000111640.15 | protein_coding | GAPDH | No | No | 2597 | P04406 |
| TVIS10017582 | HBV | ENSG00000111640.15 | protein_coding | GAPDH | No | No | 2597 | P04406 |
| TVIS44033959 | HTLV-1 | ENSG00000111640.15 | protein_coding | GAPDH | No | No | 2597 | P04406 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | GAPDH |
|---|---|
| DrugBank ID | DB00157 |
| Drug Name | NADH |
| Target ID | BE0000542 |
| UniProt ID | P04406 |
| Regulation Type | |
| PubMed IDs | 16898590; 17508915; 17031544; 17194030 |
| Citations | Markova EV, Zotova NV, Savchenko AA, Titova NM, Slepov EV, Cherdantsev DV, Konovalenko AN: [Lymphocyte metabolism in patients with acute pancreatitis with different genotypes of GSTM1 and GSTT1 genes]. Biomed Khim. 2006 May-Jun;52(3):317-26.@@Ido Y: Pyridine nucleotide redox abnormalities in diabetes. Antioxid Redox Signal. 2007 Jul;9(7):931-42.@@Trost P, Fermani S, Marri L, Zaffagnini M, Falini G, Scagliarini S, Pupillo P, Sparla F: Thioredoxin-dependent regulation of photosynthetic glyceraldehyde-3-phosphate dehydrogenase: autonomous vs. CP12-dependent mechanisms. Photosynth Res. 2006 Sep;89(2-3):263-75. Epub 2006 Sep 22.@@Swearengin TA, Fibuch EE, Seidler NW: Sevoflurane modulates the activity of glyceraldehyde 3-phosphate dehydrogenase. J Enzyme Inhib Med Chem. 2006 Oct;21(5):575-9. |
| Groups | Approved; Nutraceutical |
| Direct Classification | (5'->5')-dinucleotides |
| SMILES | NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O |
| Pathways | Ethylmalonic Encephalopathy; 3-Methylglutaconic Aciduria Type III; Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency); Caffeine Metabolism; Fructose and Mannose Degradation; Isovaleric Aciduria; Lysine Degradation; Methylmalonic Aciduria Due to Cobalamin-Related Disorders; Glycerol Phosphate Shuttle; Zellweger Syndrome; Propionic Acidemia; Glycolysis; Xanthine Dehydrogenase Deficiency (Xanthinuria); S-Adenosylhomocysteine (SAH) Hydrolase Deficiency; Tryptophan Metabolism; Glutaric Aciduria Type I; 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I; Glycine N-Methyltransferase Deficiency; Dimethylglycine Dehydrogenase Deficiency; Androgen and Estrogen Metabolism; Nucleotide Sugars Metabolism; 3-Methylglutaconic Aciduria Type IV; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Malate-Aspartate Shuttle; Folate Metabolism; Valine, Leucine, and Isoleucine Degradation; Maple Syrup Urine Disease; Glycerol Kinase Deficiency; Adenylosuccinate Lyase Deficiency; Cysteine Metabolism |
| PharmGKB | PA164755085 |
| ChEMBL | CHEMBL1234616 |
