| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46001062 | BKPyv | ENSG00000112964.14 | protein_coding | GHR | No | No | 2690 | A0A087X0H5 A0A087X162 P10912 |
| TVIS46001286 | BKPyv | ENSG00000112964.14 | protein_coding | GHR | No | No | 2690 | A0A087X0H5 A0A087X162 P10912 |
| TVIS10005296 | HBV | ENSG00000112964.14 | protein_coding | GHR | No | No | 2690 | A0A087X0H5 A0A087X162 P10912 |
| TVIS10005297 | HBV | ENSG00000112964.14 | protein_coding | GHR | No | No | 2690 | A0A087X0H5 A0A087X162 P10912 |
| TVIS10011806 | HBV | ENSG00000112964.14 | protein_coding | GHR | No | No | 2690 | A0A087X0H5 A0A087X162 P10912 |
| TVIS10011807 | HBV | ENSG00000112964.14 | protein_coding | GHR | No | No | 2690 | A0A087X0H5 A0A087X162 P10912 |
| TVIS10050761 | HBV | ENSG00000112964.14 | protein_coding | GHR | No | No | 2690 | A0A087X0H5 A0A087X162 P10912 |
| TVIS10049007 | HBV | ENSG00000112964.14 | protein_coding | GHR | No | No | 2690 | A0A087X0H5 A0A087X162 P10912 |
| TVIS10049259 | HBV | ENSG00000112964.14 | protein_coding | GHR | No | No | 2690 | A0A087X0H5 A0A087X162 P10912 |
| TVIS30082890 | HIV | ENSG00000112964.14 | protein_coding | GHR | No | No | 2690 | A0A087X0H5 A0A087X162 P10912 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GHR |
|---|---|
| DrugBank ID | DB00052 |
| Drug Name | Somatotropin |
| Target ID | BE0000075 |
| UniProt ID | P10912 |
| Regulation Type | ligand |
| PubMed IDs | 16917171; 16965663; 17082603; 17128263; 17133434; 11752352; 22291494 |
| Citations | Walenkamp MJ, Wit JM: Genetic disorders in the growth hormone - insulin-like growth factor-I axis. Horm Res. 2006;66(5):221-30.@@Wu XY, Xu Z, Chen C, Liu FK, Li JS: [Correlation of growth hormone receptor expression to preoperative radiosensitivity of rectal cancer patients]. Ai Zheng. 2006 Sep;25(9):1162-7.@@Adriani M, Garbi C, Amodio G, Russo I, Giovannini M, Amorosi S, Matrecano E, Cosentini E, Candotti F, Pignata C: Functional interaction of common gamma-chain and growth hormone receptor signaling apparatus. J Immunol. 2006 Nov 15;177(10):6889-95.@@Choi JH, Kim HS, Kim SH, Yang YR, Bae YS, Chang JS, Kwon HM, Ryu SH, Suh PG: Phospholipase Cgamma1 negatively regulates growth hormone signalling by forming a ternary complex with Jak2 and protein tyrosine phosphatase-1B. Nat Cell Biol. 2006 Dec;8(12):1389-97. Epub 2006 Nov 26.@@Bernstein RM, Leigh SR, Donovan SM, Monaco MH: Hormones and body size evolution in papionin primates. Am J Phys Anthropol. 2007 Feb;132(2):247-60.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Reh CS, Geffner ME: Somatotropin in the treatment of growth hormone deficiency and Turner syndrome in pediatric patients: a review. Clin Pharmacol. 2010;2:111-22. doi: 10.2147/CPAA.S6525. Epub 2010 Jun 1. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA451446 |
| ChEMBL | CHEMBL1201621 |
