| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46000206 | BKPyv | ENSG00000065325.13 | protein_coding | GLP2R | No | No | 9340 | O95838 |
| TVIS10001100 | HBV | ENSG00000065325.13 | protein_coding | GLP2R | No | No | 9340 | O95838 |
| TVIS10024233 | HBV | ENSG00000065325.13 | protein_coding | GLP2R | No | No | 9340 | O95838 |
| TVIS10027729 | HBV | ENSG00000065325.13 | protein_coding | GLP2R | No | No | 9340 | O95838 |
| TVIS10049523 | HBV | ENSG00000065325.13 | protein_coding | GLP2R | No | No | 9340 | O95838 |
| TVIS20032491 | HPV | ENSG00000065325.13 | protein_coding | GLP2R | No | No | 9340 | O95838 |
| TVIS44001070 | HTLV-1 | ENSG00000065325.13 | protein_coding | GLP2R | No | No | 9340 | O95838 |
| TVIS44001552 | HTLV-1 | ENSG00000065325.13 | protein_coding | GLP2R | No | No | 9340 | O95838 |
| TVIS44008076 | HTLV-1 | ENSG00000065325.13 | protein_coding | GLP2R | No | No | 9340 | O95838 |
| TVIS44030635 | HTLV-1 | ENSG00000065325.13 | protein_coding | GLP2R | No | No | 9340 | O95838 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GLP2R |
|---|---|
| DrugBank ID | DB00040 |
| Drug Name | Glucagon |
| Target ID | BE0002134 |
| UniProt ID | O95838 |
| Regulation Type | agonist |
| PubMed IDs | 17139284; 17016423; 11212269; 9990065; 15817468; 12529935 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Boushey RP, Yusta B, Drucker DJ: Glucagon-like peptide (GLP)-2 reduces chemotherapy-associated mortality and enhances cell survival in cells expressing a transfected GLP-2 receptor. Cancer Res. 2001 Jan 15;61(2):687-93.@@Munroe DG, Gupta AK, Kooshesh F, Vyas TB, Rizkalla G, Wang H, Demchyshyn L, Yang ZJ, Kamboj RK, Chen H, McCallum K, Sumner-Smith M, Drucker DJ, Crivici A: Prototypic G protein-coupled receptor for the intestinotrophic factor glucagon-like peptide 2. Proc Natl Acad Sci U S A. 1999 Feb 16;96(4):1569-73.@@Estall JL, Koehler JA, Yusta B, Drucker DJ: The glucagon-like peptide-2 receptor C terminus modulates beta-arrestin-2 association but is dispensable for ligand-induced desensitization, endocytosis, and G-protein-dependent effector activation. J Biol Chem. 2005 Jun 10;280(23):22124-34. Epub 2005 Apr 6.@@Brubaker PL, Drucker DJ: Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors. Receptors Channels. 2002;8(3-4):179-88. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA164779052 |
| ChEMBL | CHEMBL266481 |
