| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10018682 | HBV | ENSG00000135821.20 | protein_coding | GLUL | No | No | 2752 | P15104 |
| TVIS44037510 | HTLV-1 | ENSG00000135821.20 | protein_coding | GLUL | No | No | 2752 | P15104 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GLUL |
|---|---|
| DrugBank ID | DB00130 |
| Drug Name | L-Glutamine |
| Target ID | BE0002240 |
| UniProt ID | P15104 |
| Regulation Type | product of |
| PubMed IDs | 16326016; 16382338; 16484281; 16530878; 16547651 |
| Citations | Mong JA, Blutstein T: Estradiol modulation of astrocytic form and function: implications for hormonal control of synaptic communication. Neuroscience. 2006;138(3):967-75. Epub 2005 Dec 2.@@Rose C, Felipo V: Limited capacity for ammonia removal by brain in chronic liver failure: potential role of nitric oxide. Metab Brain Dis. 2005 Dec;20(4):275-83.@@Miguel-Hidalgo JJ: Withdrawal from free-choice ethanol consumption results in increased packing density of glutamine synthetase-immunoreactive astrocytes in the prelimbic cortex of alcohol-preferring rats. Alcohol Alcohol. 2006 Jul-Aug;41(4):379-85. Epub 2006 Feb 16.@@Chatauret N, Desjardins P, Zwingmann C, Rose C, Rao KV, Butterworth RF: Direct molecular and spectroscopic evidence for increased ammonia removal capacity of skeletal muscle in acute liver failure. J Hepatol. 2006 Jun;44(6):1083-8. Epub 2006 Jan 4.@@Tan S, Evans R, Singh B: Herbicidal inhibitors of amino acid biosynthesis and herbicide-tolerant crops. Amino Acids. 2006 Mar;30(2):195-204. Epub 2006 Mar 20. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | L-alpha-amino acids |
| SMILES | N[C@@H](CCC(N)=O)C(O)=O |
| Pathways | Citrullinemia Type I; Lesch-Nyhan Syndrome (LNS); Xanthinuria Type I; Phenylacetate Metabolism; Tay-Sachs Disease; Purine Nucleoside Phosphorylase Deficiency; Amino Sugar Metabolism; MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy); Glutamate Metabolism; The Oncogenic Action of D-2-Hydroxyglutarate in Hydroxygluaricaciduria; Adenine Phosphoribosyltransferase Deficiency (APRT); Mercaptopurine Action Pathway; Argininosuccinic Aciduria; Xanthine Dehydrogenase Deficiency (Xanthinuria); Salla Disease/Infantile Sialic Acid Storage Disease; Hyperinsulinism-Hyperammonemia Syndrome; G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease; Glutaminolysis and Cancer; Mitochondrial DNA Depletion Syndrome; Pyrimidine Metabolism; Carbamoyl Phosphate Synthetase Deficiency; Sialuria or French Type Sialuria; Myoadenylate Deaminase Deficiency; Homocarnosinosis; The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxygluaricaciduria; Purine Metabolism; Gout or Kelley-Seegmiller Syndrome; Adenylosuccinate Lyase Deficiency; Ammonia Recycling |
| PharmGKB | PA10090 |
| ChEMBL | CHEMBL930 |
