| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30013507 | HIV | ENSG00000164850.16 | protein_coding | GPER1 | No | No | 2852 | Q99527 |
| TVIS20007078 | HPV | ENSG00000164850.16 | protein_coding | GPER1 | No | No | 2852 | Q99527 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | GPER1 |
|---|---|
| DrugBank ID | DB00783 |
| Drug Name | Estradiol |
| Target ID | BE0003446 |
| UniProt ID | Q99527 |
| Regulation Type | binder |
| PubMed IDs | 17088055; 17222505 |
| Citations | Thomas P, Dong J: Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: a potential novel mechanism of endocrine disruption. J Steroid Biochem Mol Biol. 2006 Dec;102(1-5):175-9. Epub 2006 Nov 7.@@Prossnitz ER, Arterburn JB, Sklar LA: GPR30: A G protein-coupled receptor for estrogen. Mol Cell Endocrinol. 2007 Feb;265-266:138-42. doi: 10.1016/j.mce.2006.12.010. Epub 2007 Jan 11. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Estrogens and derivatives |
| SMILES | [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@]1([H])C3=C(CC[C@@]21[H])C=C(O)C=C3 |
| Pathways | Estrone Metabolism; Aromatase Deficiency; Androgen and Estrogen Metabolism; 17-beta Hydroxysteroid Dehydrogenase III Deficiency |
| PharmGKB | PA449503 |
| ChEMBL | CHEMBL135 |
