Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10001642HBVENSG00000224586.7protein_codingGPX5NoNo2880O75715
TVIS10023667HBVENSG00000224586.7protein_codingGPX5NoNo2880O75715
TVIS10030539HBVENSG00000224586.7protein_codingGPX5NoNo2880O75715
TCGA Plot Options
Drug Information
GeneGPX5
DrugBank IDDB00143
Drug NameGlutathione
Target IDBE0009997
UniProt IDQ8TED1
Regulation Type
PubMed IDs18498225
CitationsToppo S, Vanin S, Bosello V, Tosatto SC: Evolutionary and structural insights into the multifaceted glutathione peroxidase (Gpx) superfamily. Antioxid Redox Signal. 2008 Sep;10(9):1501-14. doi: 10.1089/ars.2008.2057.
GroupsApproved; Investigational; Nutraceutical
Direct ClassificationPeptides
SMILESN[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
PathwaysArachidonic Acid Metabolism; Flurbiprofen Action Pathway; 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency; Oxaprozin Action Pathway; Rofecoxib Action Pathway; Pyruvate Kinase Deficiency; Acetaminophen Metabolism Pathway; Mefenamic Acid Action Pathway; Bromfenac Action Pathway; 5-Oxoprolinuria; gamma-Glutamyltransferase Deficiency; Naproxen Action Pathway; Sulindac Action Pathway; Glutathione Synthetase Deficiency; Piroxicam Action Pathway; Nabumetone Action Pathway; 2-Hydroxyglutric Aciduria (D and L Form); Meloxicam Action Pathway; Cyclophosphamide Action Pathway; Succinic Semialdehyde Dehydrogenase Deficiency; Valdecoxib Action Pathway; Ketorolac Action Pathway; 5-Oxoprolinase Deficiency; Acetylsalicylic Acid Action Pathway; Antipyrine Action Pathway; Glutathione Metabolism; Diclofenac Action Pathway; Homocarnosinosis; Cyclophosphamide Metabolism Pathway; Nepafenac Action Pathway
PharmGKBPA449780
ChEMBLCHEMBL1543