| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10006103 | HBV | ENSG00000163873.10 | protein_coding | GRIK3 | No | No | 2899 | Q13003 |
| TVIS10006104 | HBV | ENSG00000163873.10 | protein_coding | GRIK3 | No | No | 2899 | Q13003 |
| TVIS30085912 | HIV | ENSG00000163873.10 | protein_coding | GRIK3 | No | No | 2899 | Q13003 |
| TVIS30023246 | HIV | ENSG00000163873.10 | protein_coding | GRIK3 | No | No | 2899 | Q13003 |
| TVIS20006209 | HPV | ENSG00000163873.10 | protein_coding | GRIK3 | No | No | 2899 | Q13003 |
| TVIS20047579 | HPV | ENSG00000163873.10 | protein_coding | GRIK3 | No | No | 2899 | Q13003 |
| TVIS20047672 | HPV | ENSG00000163873.10 | protein_coding | GRIK3 | No | No | 2899 | Q13003 |
| TVIS20046817 | HPV | ENSG00000163873.10 | protein_coding | GRIK3 | No | No | 2899 | Q13003 |
| TVIS44003519 | HTLV-1 | ENSG00000163873.10 | protein_coding | GRIK3 | No | No | 2899 | Q13003 |
| TVIS44024554 | HTLV-1 | ENSG00000163873.10 | protein_coding | GRIK3 | No | No | 2899 | Q13003 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRIK3 |
|---|---|
| DrugBank ID | DB00142 |
| Drug Name | Glutamic acid |
| Target ID | BE0000832 |
| UniProt ID | Q13003 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 1371217; 11058796; 8622118 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Bettler B, Egebjerg J, Sharma G, Pecht G, Hermans-Borgmeyer I, Moll C, Stevens CF, Heinemann S: Cloning of a putative glutamate receptor: a low affinity kainate-binding subunit. Neuron. 1992 Feb;8(2):257-65.@@Takeda M, Haga M, Yamada H, Kinoshita M, Otsuka M, Tsuboi S, Moriyama Y: Ionotropic glutamate receptors expressed in human retinoblastoma Y79 cells. Neurosci Lett. 2000 Nov 17;294(2):97-100.@@Stuhmer T, Amar M, Harvey RJ, Bermudez I, van Minnen J, Darlison MG: Structure and pharmacological properties of a molluscan glutamate-gated cation channel and its likely role in feeding behavior. J Neurosci. 1996 May 1;16(9):2869-80. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | Histidinemia; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Purine Nucleoside Phosphorylase Deficiency; Tyrosine Metabolism; Ketoprofen Action Pathway; Glutamate Metabolism; Argininosuccinic Aciduria; Salla Disease/Infantile Sialic Acid Storage Disease; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Celecoxib Action Pathway; Glycine and Serine Metabolism; Suprofen Action Pathway; Indomethacin Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Sialuria or French Type Sialuria; Ibuprofen Action Pathway; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Arginine and Proline Metabolism; Purine Metabolism; Diflunisal Action Pathway; Etodolac Action Pathway; Ammonia Recycling |
| PharmGKB | PA449776 |
| ChEMBL | CHEMBL575060 |
