| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10052790 | HBV | ENSG00000105737.10 | protein_coding | GRIK5 | No | No | 2901 | Q16478 |
| TVIS30074948 | HIV | ENSG00000105737.10 | protein_coding | GRIK5 | No | No | 2901 | Q16478 |
| TVIS30048725 | HIV | ENSG00000105737.10 | protein_coding | GRIK5 | No | No | 2901 | Q16478 |
| TVIS30048726 | HIV | ENSG00000105737.10 | protein_coding | GRIK5 | No | No | 2901 | Q16478 |
| TVIS44027661 | HTLV-1 | ENSG00000105737.10 | protein_coding | GRIK5 | No | No | 2901 | Q16478 |
| TVIS44024004 | HTLV-1 | ENSG00000105737.10 | protein_coding | GRIK5 | No | No | 2901 | Q16478 |
| TVIS44027662 | HTLV-1 | ENSG00000105737.10 | protein_coding | GRIK5 | No | No | 2901 | Q16478 |
| TVIS44042597 | HTLV-1 | ENSG00000105737.10 | protein_coding | GRIK5 | No | No | 2901 | Q16478 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRIK5 |
|---|---|
| DrugBank ID | DB00142 |
| Drug Name | Glutamic acid |
| Target ID | BE0000828 |
| UniProt ID | Q16478 |
| Regulation Type | |
| PubMed IDs | 17139284; 17016423; 11058796; 2850065 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Takeda M, Haga M, Yamada H, Kinoshita M, Otsuka M, Tsuboi S, Moriyama Y: Ionotropic glutamate receptors expressed in human retinoblastoma Y79 cells. Neurosci Lett. 2000 Nov 17;294(2):97-100.@@Murphy DE, Hutchison AJ, Hurt SD, Williams M, Sills MA: Characterization of the binding of [3H]-CGS 19755: a novel N-methyl-D-aspartate antagonist with nanomolar affinity in rat brain. Br J Pharmacol. 1988 Nov;95(3):932-8. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | Histidinemia; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Purine Nucleoside Phosphorylase Deficiency; Tyrosine Metabolism; Ketoprofen Action Pathway; Glutamate Metabolism; Argininosuccinic Aciduria; Salla Disease/Infantile Sialic Acid Storage Disease; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Celecoxib Action Pathway; Glycine and Serine Metabolism; Suprofen Action Pathway; Indomethacin Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Sialuria or French Type Sialuria; Ibuprofen Action Pathway; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Arginine and Proline Metabolism; Purine Metabolism; Diflunisal Action Pathway; Etodolac Action Pathway; Ammonia Recycling |
| PharmGKB | PA449776 |
| ChEMBL | CHEMBL575060 |
