| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10009191 | HBV | ENSG00000152822.15 | protein_coding | GRM1 | No | No | 2911 | Q13255 |
| TVIS10014954 | HBV | ENSG00000152822.15 | protein_coding | GRM1 | No | No | 2911 | Q13255 |
| TVIS10036033 | HBV | ENSG00000152822.15 | protein_coding | GRM1 | No | No | 2911 | Q13255 |
| TVIS10030691 | HBV | ENSG00000152822.15 | protein_coding | GRM1 | No | No | 2911 | Q13255 |
| TVIS10020569 | HBV | ENSG00000152822.15 | protein_coding | GRM1 | No | No | 2911 | Q13255 |
| TVIS10041684 | HBV | ENSG00000152822.15 | protein_coding | GRM1 | No | No | 2911 | Q13255 |
| TVIS10041685 | HBV | ENSG00000152822.15 | protein_coding | GRM1 | No | No | 2911 | Q13255 |
| TVIS10052803 | HBV | ENSG00000152822.15 | protein_coding | GRM1 | No | No | 2911 | Q13255 |
| TVIS10049009 | HBV | ENSG00000152822.15 | protein_coding | GRM1 | No | No | 2911 | Q13255 |
| TVIS30083880 | HIV | ENSG00000152822.15 | protein_coding | GRM1 | No | No | 2911 | Q13255 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRM1 |
|---|---|
| DrugBank ID | DB00142 |
| Drug Name | Glutamic acid |
| Target ID | BE0000824 |
| UniProt ID | Q13255 |
| Regulation Type | |
| PubMed IDs | 17360958; 16751798; 17331504 |
| Citations | Suzuki G, Kimura T, Satow A, Kaneko N, Fukuda J, Hikichi H, Sakai N, Maehara S, Kawagoe-Takaki H, Hata M, Azuma T, Ito S, Kawamoto H, Ohta H: Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl- 3,6-dihydropyridine-1(2H)-carboxamide (FTIDC). J Pharmacol Exp Ther. 2007 Jun;321(3):1144-53. Epub 2007 Mar 14.@@Chiocchetti A, Miglio G, Mesturini R, Varsaldi F, Mocellin M, Orilieri E, Dianzani C, Fantozzi R, Dianzani U, Lombardi G: Group I mGlu receptor stimulation inhibits activation-induced cell death of human T lymphocytes. Br J Pharmacol. 2006 Jul;148(6):760-8. Epub 2006 Jun 5.@@San Gabriel AM, Maekawa T, Uneyama H, Yoshie S, Torii K: mGluR1 in the fundic glands of rat stomach. FEBS Lett. 2007 Mar 20;581(6):1119-23. Epub 2007 Feb 22. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | Histidinemia; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Purine Nucleoside Phosphorylase Deficiency; Tyrosine Metabolism; Ketoprofen Action Pathway; Glutamate Metabolism; Argininosuccinic Aciduria; Salla Disease/Infantile Sialic Acid Storage Disease; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Celecoxib Action Pathway; Glycine and Serine Metabolism; Suprofen Action Pathway; Indomethacin Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Sialuria or French Type Sialuria; Ibuprofen Action Pathway; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Arginine and Proline Metabolism; Purine Metabolism; Diflunisal Action Pathway; Etodolac Action Pathway; Ammonia Recycling |
| PharmGKB | PA449776 |
| ChEMBL | CHEMBL575060 |
