| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30086869 | HIV | ENSG00000124493.14 | protein_coding | GRM4 | No | No | 2914 | A1L4F9 B7ZLU9 Q14833 |
| TVIS30086319 | HIV | ENSG00000124493.14 | protein_coding | GRM4 | No | No | 2914 | A1L4F9 B7ZLU9 Q14833 |
| TVIS30080842 | HIV | ENSG00000124493.14 | protein_coding | GRM4 | No | No | 2914 | A1L4F9 B7ZLU9 Q14833 |
| TVIS30082191 | HIV | ENSG00000124493.14 | protein_coding | GRM4 | No | No | 2914 | A1L4F9 B7ZLU9 Q14833 |
| TVIS30064521 | HIV | ENSG00000124493.14 | protein_coding | GRM4 | No | No | 2914 | A1L4F9 B7ZLU9 Q14833 |
| TVIS20011567 | HPV | ENSG00000124493.14 | protein_coding | GRM4 | No | No | 2914 | A1L4F9 B7ZLU9 Q14833 |
| TVIS20026247 | HPV | ENSG00000124493.14 | protein_coding | GRM4 | No | No | 2914 | A1L4F9 B7ZLU9 Q14833 |
| TVIS20019207 | HPV | ENSG00000124493.14 | protein_coding | GRM4 | No | No | 2914 | A1L4F9 B7ZLU9 Q14833 |
| TVIS44011413 | HTLV-1 | ENSG00000124493.14 | protein_coding | GRM4 | No | No | 2914 | A1L4F9 B7ZLU9 Q14833 |
| TVIS44048994 | HTLV-1 | ENSG00000124493.14 | protein_coding | GRM4 | No | No | 2914 | A1L4F9 B7ZLU9 Q14833 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | GRM4 |
|---|---|
| DrugBank ID | DB00142 |
| Drug Name | Glutamic acid |
| Target ID | BE0000833 |
| UniProt ID | Q14833 |
| Regulation Type | |
| PubMed IDs | 17360958 |
| Citations | Suzuki G, Kimura T, Satow A, Kaneko N, Fukuda J, Hikichi H, Sakai N, Maehara S, Kawagoe-Takaki H, Hata M, Azuma T, Ito S, Kawamoto H, Ohta H: Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl- 3,6-dihydropyridine-1(2H)-carboxamide (FTIDC). J Pharmacol Exp Ther. 2007 Jun;321(3):1144-53. Epub 2007 Mar 14. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | Histidinemia; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Purine Nucleoside Phosphorylase Deficiency; Tyrosine Metabolism; Ketoprofen Action Pathway; Glutamate Metabolism; Argininosuccinic Aciduria; Salla Disease/Infantile Sialic Acid Storage Disease; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Celecoxib Action Pathway; Glycine and Serine Metabolism; Suprofen Action Pathway; Indomethacin Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Sialuria or French Type Sialuria; Ibuprofen Action Pathway; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Arginine and Proline Metabolism; Purine Metabolism; Diflunisal Action Pathway; Etodolac Action Pathway; Ammonia Recycling |
| PharmGKB | PA449776 |
| ChEMBL | CHEMBL575060 |
