| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30073707 | HIV | ENSG00000165704.15 | protein_coding | HPRT1 | No | No | 3251 | A0A140VJL3 P00492 |
| TVIS20064427 | HPV | ENSG00000165704.15 | protein_coding | HPRT1 | No | No | 3251 | A0A140VJL3 P00492 |
| TVIS20013444 | HPV | ENSG00000165704.15 | protein_coding | HPRT1 | No | No | 3251 | A0A140VJL3 P00492 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HPRT1 |
|---|---|
| DrugBank ID | DB01033 |
| Drug Name | Mercaptopurine |
| Target ID | BE0000077 |
| UniProt ID | P00492 |
| Regulation Type | inhibitor |
| PubMed IDs | 15354273 |
| Citations | Dubinsky MC: Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, efficacy, and safety. Clin Gastroenterol Hepatol. 2004 Sep;2(9):731-43. |
| Groups | Approved |
| Direct Classification | Purinethiones |
| SMILES | S=C1N=CNC2=C1NC=N2 |
| Pathways | Mercaptopurine Metabolism Pathway; Mercaptopurine Action Pathway; Thioguanine Action Pathway; Azathioprine Action Pathway; Azathioprine Metabolism Pathway |
| PharmGKB | PA450379 |
| ChEMBL | CHEMBL1425 |
