| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30022575 | HIV | ENSG00000142798.20 | protein_coding | HSPG2 | No | No | 3339 | P98160 |
| TVIS20036000 | HPV | ENSG00000142798.20 | protein_coding | HSPG2 | No | No | 3339 | P98160 |
| TVIS20045288 | HPV | ENSG00000142798.20 | protein_coding | HSPG2 | No | No | 3339 | P98160 |
| TVIS44018613 | HTLV-1 | ENSG00000142798.20 | protein_coding | HSPG2 | No | No | 3339 | P98160 |
| TVIS44034479 | HTLV-1 | ENSG00000142798.20 | protein_coding | HSPG2 | No | No | 3339 | P98160 |
| TVIS44043993 | HTLV-1 | ENSG00000142798.20 | protein_coding | HSPG2 | No | No | 3339 | P98160 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HSPG2 |
|---|---|
| DrugBank ID | DB00039 |
| Drug Name | Palifermin |
| Target ID | BE0001031 |
| UniProt ID | P98160 |
| Regulation Type | ligand |
| PubMed IDs | 10593896; 9788974; 16989989; 14753849; 9094999 |
| Citations | Berman B, Ostrovsky O, Shlissel M, Lang T, Regan D, Vlodavsky I, Ishai-Michaeli R, Ron D: Similarities and differences between the effects of heparin and glypican-1 on the bioactivity of acidic fibroblast growth factor and the keratinocyte growth factor. J Biol Chem. 1999 Dec 17;274(51):36132-8.@@Sharma B, Handler M, Eichstetter I, Whitelock JM, Nugent MA, Iozzo RV: Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo. J Clin Invest. 1998 Oct 15;102(8):1599-608.@@Iwabuchi T, Goetinck PF: Syndecan-4 dependent FGF stimulation of mouse vibrissae growth. Mech Dev. 2006 Nov;123(11):831-41. Epub 2006 Aug 12.@@Asada N, Tanaka Y, Hayashido Y, Toratani S, Kan M, Kitamoto M, Nakanishi T, Kajiyama G, Chayama K, Okamoto T: Expression of fibroblast growth factor receptor genes in human hepatoma-derived cell lines. In Vitro Cell Dev Biol Anim. 2003 Jul-Aug;39(7):321-8.@@Friedl A, Chang Z, Tierney A, Rapraeger AC: Differential binding of fibroblast growth factor-2 and -7 to basement membrane heparan sulfate: comparison of normal and abnormal human tissues. Am J Pathol. 1997 Apr;150(4):1443-55. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA164744014 |
| ChEMBL | CHEMBL1201821 |
