| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44010428 | HTLV-1 | ENSG00000166736.12 | protein_coding | HTR3A | No | No | 3359 | P46098 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | HTR3A |
|---|---|
| DrugBank ID | DB00333 |
| Drug Name | Methadone |
| Target ID | BE0000311 |
| UniProt ID | P46098 |
| Regulation Type | antagonist |
| PubMed IDs | 19131665 |
| Citations | Deeb TZ, Sharp D, Hales TG: Direct subunit-dependent multimodal 5-hydroxytryptamine3 receptor antagonism by methadone. Mol Pharmacol. 2009 Apr;75(4):908-17. doi: 10.1124/mol.108.053322. Epub 2009 Jan 8. |
| Groups | Approved |
| Direct Classification | Diphenylmethanes |
| SMILES | CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C1=CC=CC=C1 |
| Pathways | Methadone Metabolism Pathway; Methadone Action Pathway |
| PharmGKB | PA450401 |
| ChEMBL | CHEMBL651 |
