| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30017466 | HIV | ENSG00000168135.4 | protein_coding | KCNJ4 | No | No | 3761 | P48050 Q58F07 |
| TVIS44028432 | HTLV-1 | ENSG00000168135.4 | protein_coding | KCNJ4 | No | No | 3761 | P48050 Q58F07 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNJ4 |
|---|---|
| DrugBank ID | DB01136 |
| Drug Name | Carvedilol |
| Target ID | BE0005187 |
| UniProt ID | P48050 |
| Regulation Type | inhibitor |
| PubMed IDs | 21663737 |
| Citations | Ferrer T, Ponce-Balbuena D, Lopez-Izquierdo A, Arechiga-Figueroa IA, de Boer TP, van der Heyden MA, Sanchez-Chapula JA: Carvedilol inhibits Kir2.3 channels by interference with PIP(2)-channel interaction. Eur J Pharmacol. 2011 Oct 1;668(1-2):72-7. doi: 10.1016/j.ejphar.2011.05.067. Epub 2011 Jun 6. |
| Groups | Approved; Investigational |
| Direct Classification | Carbazoles |
| SMILES | COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=C1C1=CC=CC=C1N2 |
| Pathways | Carvedilol Action Pathway |
| PharmGKB | PA448817 |
| ChEMBL | CHEMBL723 |
