| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10015059 | HBV | ENSG00000117013.17 | protein_coding | KCNQ4 | No | No | 9132 | P56696 |
| TVIS10025811 | HBV | ENSG00000117013.17 | protein_coding | KCNQ4 | No | No | 9132 | P56696 |
| TVIS20016304 | HPV | ENSG00000117013.17 | protein_coding | KCNQ4 | No | No | 9132 | P56696 |
| TVIS20047281 | HPV | ENSG00000117013.17 | protein_coding | KCNQ4 | No | No | 9132 | P56696 |
| TVIS20016049 | HPV | ENSG00000117013.17 | protein_coding | KCNQ4 | No | No | 9132 | P56696 |
| TVIS20047292 | HPV | ENSG00000117013.17 | protein_coding | KCNQ4 | No | No | 9132 | P56696 |
| TVIS20033048 | HPV | ENSG00000117013.17 | protein_coding | KCNQ4 | No | No | 9132 | P56696 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KCNQ4 |
|---|---|
| DrugBank ID | DB04953 |
| Drug Name | Ezogabine |
| Target ID | BE0002399 |
| UniProt ID | P56696 |
| Regulation Type | |
| PubMed IDs | 17184917; 11378159; 16713428 |
| Citations | Hirano K, Kuratani K, Fujiyoshi M, Tashiro N, Hayashi E, Kinoshita M: Kv7.2-7.5 voltage-gated potassium channel (KCNQ2-5) opener, retigabine, reduces capsaicin-induced visceral pain in mice. Neurosci Lett. 2007 Feb 14;413(2):159-62. Epub 2006 Dec 20.@@Schroder RL, Jespersen T, Christophersen P, Strobaek D, Jensen BS, Olesen SP: KCNQ4 channel activation by BMS-204352 and retigabine. Neuropharmacology. 2001 Jun;40(7):888-98.@@Borlak J, Gasparic A, Locher M, Schupke H, Hermann R: N-Glucuronidation of the antiepileptic drug retigabine: results from studies with human volunteers, heterologously expressed human UGTs, human liver, kidney, and liver microsomal membranes of Crigler-Najjar type II. Metabolism. 2006 Jun;55(6):711-21. |
| Groups | Approved; Investigational |
| Direct Classification | Phenylbenzamines |
| SMILES | CCOC(=O)NC1=C(N)C=C(NCC2=CC=C(F)C=C2)C=C1 |
| Pathways | |
| PharmGKB | PA144997862 |
| ChEMBL | CHEMBL41355 |
