| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30004718 | HIV | ENSG00000079999.14 | protein_coding | KEAP1 | No | Yes | 9817 | Q14145 |
| TVIS20020750 | HPV | ENSG00000079999.14 | protein_coding | KEAP1 | No | Yes | 9817 | Q14145 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | KEAP1 |
|---|---|
| DrugBank ID | DB08908 |
| Drug Name | Dimethyl fumarate |
| Target ID | BE0004756 |
| UniProt ID | Q14145 |
| Regulation Type | binder |
| PubMed IDs | 23056222 |
| Citations | Oh CJ, Kim JY, Choi YK, Kim HJ, Jeong JY, Bae KH, Park KG, Lee IK: Dimethylfumarate attenuates renal fibrosis via NF-E2-related factor 2-mediated inhibition of transforming growth factor-beta/Smad signaling. PLoS One. 2012;7(10):e45870. doi: 10.1371/journal.pone.0045870. Epub 2012 Oct 8. |
| Groups | Approved; Investigational |
| Direct Classification | Fatty acid esters |
| SMILES | [H]C(=C([H])C(=O)OC)C(=O)OC |
| Pathways | |
| PharmGKB | PA166152838 |
| ChEMBL | CHEMBL2107333 |
