Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10025391HBVENSG00000205629.12protein_codingLCMT1NoNo51451Q9UIC8
TVIS30040648HIVENSG00000205629.12protein_codingLCMT1NoNo51451Q9UIC8
TVIS30040649HIVENSG00000205629.12protein_codingLCMT1NoNo51451Q9UIC8
TVIS20000728HPVENSG00000205629.12protein_codingLCMT1NoNo51451Q9UIC8
TVIS20032311HPVENSG00000205629.12protein_codingLCMT1NoNo51451Q9UIC8
TVIS44017875HTLV-1ENSG00000205629.12protein_codingLCMT1NoNo51451Q9UIC8
TCGA Plot Options
Drug Information
GeneLCMT1
DrugBank IDDB00149
Drug NameLeucine
Target IDBE0000450
UniProt IDQ9UIC8
Regulation Type
PubMed IDs17139284; 17016423
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.
GroupsInvestigational; Nutraceutical
Direct ClassificationLeucine and derivatives
SMILESCC(C)C[C@H](N)C(O)=O
Pathways3-Methylglutaconic Aciduria Type III; 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Demeclocycline Action Pathway; Josamycin Action Pathway; Gentamicin Action Pathway; Lincomycin Action Pathway; Isobutyryl-CoA Dehydrogenase Deficiency; Methacycline Action Pathway; Clarithromycin Action Pathway; Paromomycin Action Pathway; Minocycline Action Pathway; Lymecycline Action Pathway; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency; Glutaminolysis and Cancer; Troleandomycin Action Pathway; Amikacin Action Pathway; Methylmalonic Aciduria; Oxytetracycline Action Pathway; Tetracycline Action Pathway; Spectinomycin Action Pathway; Doxycycline Action Pathway; Telithromycin Action Pathway; Roxithromycin Action Pathway; Tigecycline Action Pathway; Valine, Leucine, and Isoleucine Degradation; Arbekacin Action Pathway; Isovaleric Acidemia; Chloramphenicol Action Pathway
PharmGKBPA450197
ChEMBLCHEMBL291962