| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10047830 | HBV | ENSG00000121897.15 | protein_coding | LIAS | No | No | 11019 | B4E0L7 O43766 Q6P5Q6 |
| TVIS10047831 | HBV | ENSG00000121897.15 | protein_coding | LIAS | No | No | 11019 | B4E0L7 O43766 Q6P5Q6 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | LIAS |
|---|---|
| DrugBank ID | DB00166 |
| Drug Name | Lipoic acid |
| Target ID | BE0002327 |
| UniProt ID | O43766 |
| Regulation Type | |
| PubMed IDs | 11389890; 9808738; 10403368; 15225307; 16246025 |
| Citations | Morikawa T, Yasuno R, Wada H: Do mammalian cells synthesize lipoic acid? Identification of a mouse cDNA encoding a lipoic acid synthase located in mitochondria. FEBS Lett. 2001 Jun 1;498(1):16-21.@@Yasuno R, Wada H: Biosynthesis of lipoic acid in Arabidopsis: cloning and characterization of the cDNA for lipoic acid synthase. Plant Physiol. 1998 Nov;118(3):935-43.@@Ollagnier-de Choudens S, Fontecave M: The lipoate synthase from Escherichia coli is an iron-sulfur protein. FEBS Lett. 1999 Jun 18;453(1-2):25-8.@@Wrenger C, Muller S: The human malaria parasite Plasmodium falciparum has distinct organelle-specific lipoylation pathways. Mol Microbiol. 2004 Jul;53(1):103-13.@@Gunther S, McMillan PJ, Wallace LJ, Muller S: Plasmodium falciparum possesses organelle-specific alpha-keto acid dehydrogenase complexes and lipoylation pathways. Biochem Soc Trans. 2005 Nov;33(Pt 5):977-80. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Lipoic acids and derivatives |
| SMILES | OC(=O)CCCC[C@@H]1CCSS1 |
| Pathways | |
| PharmGKB | PA164776929 |
| ChEMBL | CHEMBL134342 |
